Yeast Sequencing Report

Yeast sequencing reports. Gcs1, a gene encoding γ-glutamylcysteine synthetase in the fission yeast Schizosaccharomyces pombe

  1. Anke Coblenz,
  2. Klaus Wolf*

Article first published online: 29 JAN 2004

DOI: 10.1002/yea.320111207

Issue

Yeast

Yeast

Volume 11, Issue 12, pages 1171–1177, 30 September 1995

Additional Information

How to Cite

Coblenz, A. and Wolf, K. (1995), Yeast sequencing reports. Gcs1, a gene encoding γ-glutamylcysteine synthetase in the fission yeast Schizosaccharomyces pombe. Yeast, 11: 1171–1177. doi: 10.1002/yea.320111207

Author Information

  1. Institut für Biologie IV (Mikrobiologie), Rheinisch-Westfälische Technische Hochschule Aachen, Worringer Weg, D-52056 Aachen, Germany

*Institut für Biologie IV (Mikrobiologie), Rheinisch-Westfälische Technische Hochschule Aachen, Worringer Weg, D-52056 Aachen, Germany

Publication History

  1. Issue published online: 29 JAN 2004
  2. Article first published online: 29 JAN 2004
  3. Manuscript Accepted: 20 APR 1995
  4. Manuscript Received: 1 MAR 1995

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Keywords:

  • γ-glutamylcysteine synthetase;
  • glutathione;
  • Schizosaccharomyces pombe

Abstract

By complementation of a mutant resistant to N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) we have identified the gcs1 gene, encoding a putative γ-glutamylcysteine synthetase. The gene is possibly interrupted by two introns and has 49% identical and 80% similar amino acids compared with the homologous protein from rat. In comparison with the Saccharomyces cerevisiae homologue it possesses 41% identical and 74% similar amino acids. The gsc1 sequence appears in the EMBL database under Accession Number X 85017.

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