Zintl phase compounds with large unit cells and complex anionic structures such as Yb11Sb10 hold potential for being good thermoelectric materials. Single crystals of Ge-doped Yb11Sb10 were synthesized using a molten Sn-flux technique. Single crystal X-ray diffraction data were obtained and resulted in a composition of Yb11Sb9.3Ge0.5 which was verified by microprobe. Yb11Sb9.3Ge0.5 is isostructural to Ho11Ge10, crystallizing in a body-centered, tetragonal unit cell, space group I4/mmm, with Z = 4. The unit cell parameters of Yb11Sb9.3Ge0.5 are a = 11.8813(4), c = 17.1276(13) Å with a volume of 2417.8(2) Å3. These parameters correlate well with the structural refinement of previously published Yb11Sb10. The structure consists of 16 isolated Sb3− anions, 8 dumbbells, 2 square planar rings and 44 Yb2+ cations. The Ge, doped in at 28 % occupancy, was found to be site specific, residing on the 2 square planar rings. Single crystal X-ray diffraction is most consistent with the site that makes up the square ring being less than fully occupied. The doped compound is additionally characterized by X-ray powder diffraction, differential scanning calorimetry and thermogravimetry. High temperature (300–1200 K) thermoelectric properties show that the doped compound has extremely low thermal conductivity (10–30 mW/cmK), lower than that of Yb11Sb10. Temperature dependent resistivity is consistent with a heavily doped semiconductor. Yb11Sb9.3Ge0.5 shows p-type behavior increasing from ∼22 μV/K at room temperature to ∼31 μV/K at 1140 K. The low value and the temperature dependence of the Seebeck coefficient suggest that bipolar conduction produces a compensated Seebeck coefficient and consequently a low zT.