Effects of catechins on the mouse lung carcinoma cell adhesion to the endothelial cells.
Version of Record online: 2 JAN 2013
© The Author(s) Journal compilation © 1993 International Federation for Cell Biology
Cell Biology International
Volume 17, Issue 6, pages 559–564, June 1993
How to Cite
Isemura, M., Suzuki, Y., Satoh, K., Narumi, K. and Motomiya, M. (1993), Effects of catechins on the mouse lung carcinoma cell adhesion to the endothelial cells. Cell Biology International, 17: 559–564. doi: 10.1006/cbir.1993.1099
- Issue online: 2 JAN 2013
- Version of Record online: 2 JAN 2013
- Paper received 05.01.93. Revised paper accepted 27.03.93.
- Cited By
We studied the effects of 5 kinds of catechins on the adhesion of mouse lung carcinoma 3LL cells to the monolayer of bovine lung endothelial cells. (-)-Epicatechin gallate and (-)-epigallocatechin gallate were active in inhibiting the 3LL cell adhesion, while (+)-catechin and (-)-epicatechin were inactive. (-)-Epigallocatechin showed a considerable cytotoxicity. These data suggest that the specific chemical structure is required to exert the inhibitory activity of catechins and the search for the cellular binding protein(s) bound to these inhibitory catechins would provide a clue to clarify the mechanism of interactions between tumor cells and endothelial cells.