The influence of maternal nicotine exposure on neonatal lung metabolism. Protective effect of ascorbic acid.
Article first published online: 2 JAN 2013
© The Author(s) Journal compilation © 1993 International Federation for Cell Biology
Cell Biology International
Volume 17, Issue 6, pages 579–585, June 1993
How to Cite
Maritz, G. S. (1993), The influence of maternal nicotine exposure on neonatal lung metabolism. Protective effect of ascorbic acid. Cell Biology International, 17: 579–585. doi: 10.1006/cbir.1993.1102
- Issue published online: 2 JAN 2013
- Article first published online: 2 JAN 2013
- Paper received 04.11.92 Revised paper accepted 27.03.93.
- Cited By
The aim of the present study was to establish whether ascorbic acid supplementation (1 mg/kg/body mass/day) during pregnancy and lactation will prevent the effect of maternal nicotine exposure (1 mg/kg body weight/day) on neonatal lung carbohydrate, DNA and protein metabolism. The data show that the adult lung ascorbic acid content was reduced by 76% after exposure to nicotine. In contrast, maternal nicotine exposure during pregnancy and lactation has no effect on neonatal lung ascorbic acid content. However, ascorbic acid supplementation during pregnancy and lactation prevented the adverse effects of maternal nicotine exposure on neonatal lung carbohydrate, DNA and protein metabolism.