Carbohydrate metabolism of lung tissue of suckling and adult rats.
Article first published online: 2 JAN 2013
© The Author(s) Journal compilation © 1993 International Federation for Cell Biology
Cell Biology International
Volume 17, Issue 8, pages 773–780, August 1993
How to Cite
Maritz, G. S. (1993), Carbohydrate metabolism of lung tissue of suckling and adult rats. Cell Biology International, 17: 773–780. doi: 10.1006/cbir.1993.1139
- Issue published online: 2 JAN 2013
- Article first published online: 2 JAN 2013
- Paper received 24.05.93. Paper accepted 27.06.93.
- Cited By
The carbohydrate metabolism of lung tissue of suckling (1-3 weeks) and adult (40-42 weeks) rats were investigated and compared. The results showed that the apparent km for in vitro glucose utilization was 3,13 mM for adult lung and the V max 136,99 μmol/g/h. This could not be determined for neonatal animals. The rate of glucose entry into the glycolytic pathway of adult lung was faster than in the lung of neonatal rats. However, glycogen utilization by neonatal lung was faster than by adult lung. The in vitro oxygen consumption of the lung tissue slices of both age groups were the same. It is proposed that the slower rate of glucose entry into glycolysis in lung tissue of suckling rats is due to a different hexokinase isoenzyme profile. It is also concluded that glycogen-glucose plays a major role in lung development.