The control of Ca2+ homeostasis: role of intracellular rapidly exchanging Ca2+ stores.
Article first published online: 2 JAN 2013
© The Author(s) Journal compilation © 1994 International Federation for Cell Biology
Cell Biology International
Volume 18, Issue 5, pages 301–307, May 1994
How to Cite
Villa, A. and Meldolesi, J. (1994), The control of Ca2+ homeostasis: role of intracellular rapidly exchanging Ca2+ stores. Cell Biology International, 18: 301–307. doi: 10.1006/cbir.1994.1078
- Issue published online: 2 JAN 2013
- Article first published online: 2 JAN 2013
- Cited By
The role of rapidly exchanging intracellular Ca2+ stores in the control of Ca2+ homeostasis is reviewed. The following issues are discussed: the reasons why such stores exist in eukaryotic cells; the differences between the terminal cisternae of the skeletal muscle sarcoplasmic reticulum, which have direct, physical connection with the T tubules of the plasmalemma, and the Ca2+ stores located in the depth of the cytoplasm, which are stimulated by second messengers; the cytological nature (subcompartments of the ER) of the rapidly exchanging Ca2+ stores and their functional significance. The conclusions introduce recent developments in which intracellular Ca2+ stores have been investigated also by molecular biology techniques.