A GCN-like response in Candida albicans.
Version of Record online: 2 JAN 2013
© The Author(s) Journal compilation © 1995 International Federation for Cell Biology
Cell Biology International
Volume 19, Issue 1, pages 65–70, January 1995
How to Cite
Pereira, S. A. and Livi, G. P. (1995), A GCN-like response in Candida albicans. Cell Biology International, 19: 65–70. doi: 10.1006/cbir.1995.1009
- Issue online: 2 JAN 2013
- Version of Record online: 2 JAN 2013
- Cited By
The control of amino acid and purine biosynthesis in the yeast Saccharomyces cerevisiae is mediated by the transcriptional activator GCN4. We previously identified the presence of two putative GCN4 responsive elements (GCREs) in the promoter sequence of the Candida albicans ARO3 gene, which encodes an enzyme in the aromatic amino acid pathway. We now show that amino acid deprivation results in a dramatic rise in the steady-state level of ARO3-specific mRNA, indicative of a GCN-like pathway in C. albicans.