REGULATION OF GENE EXPRESSION BY GC-RICH DNA CIS -ELEMENTS

Authors


To whom correspondence should be addressed: Prof. Janet Hapgood, Department of Biochemistry, Private Bag X1, Matieland 7602, South Africa. E-mail:JHap@maties.sun.ac.za

Abstract

GC-rich DNA cis elements are important transcriptional regulatory elements present in the promoter, enhancer and locus control regions of many eukaryotic genes from several species. This review attempts to examine the structure, function and biological significance of GC-rich cis -regulatory elements and their cognate binding proteins, with a view to understanding their role in regulation of gene expression.

Ancillary