Division of Neuroscience, Baylor College of Medicine, Houston, TX.
Mesial temporal lobe epilepsy: A pathological replay of developmental mechanisms?
Article first published online: 16 JAN 2012
2003 Société Française des Microscopies and Société Biologie Cellulaire de France
Biology of the Cell
Volume 95, Issue 6, pages 329–333, September 2003
How to Cite
Cohen, I., Navarro, V., Le Duigou, C. and Miles, R. (2003), Mesial temporal lobe epilepsy: A pathological replay of developmental mechanisms?. Biology of the Cell, 95: 329–333. doi: 10.1016/S0248-4900(03)00081-9
- Issue published online: 16 JAN 2012
- Article first published online: 16 JAN 2012
- Received 31 March 2003; accepted 19 May 2003
- Cited By
- Cell death;
Focal epilepsies of the mesial temporal lobe are often associated with a hippocampal sclerosis. Changes in Cl homeostasis and GABAergic signalling in downstream regions, may contribute to the human pathology. A review of changes in cellular and synaptic function and connectivity after de-afferentation suggests this epileptic syndrome may involve a pathological replay of developmental mechanisms.