• 1
    Augat P, Merk J, Ignatius A, Margevicius K, Bauer G, Rosenbaum D, et al. Early, full weightbearing with flexible fixation delays fracture healing. Clin Orthop 1996; 328: 194202.
  • 2
    Augat P, Merk J, Wolf S, Claes L. Mechanical stimulation by external application of cyclic tensile strains does not effectively enhance bone healing. J Orthop Trauma 2001; 15: 5460.
  • 3
    Bail HJ, Kolbeck S, Klein P, Schmidmaier G, Roenne I, Haas N, et al. Systematically administered growth hormone enhances the early phase of osteochondral defect healing. Trans Orthop Res Soc, Orlando 2000: 182.
  • 4
    Brighton CT, Hunt RM. Early histologic and ultrastructural changes in microvessels of periosteal callus. J Orthop Trauma 1997; 11: 24453.
  • 5
    Chao EY, Aro HT, Lewallen DG, Kelly PJ. The effect of rigidity on fracture healing in external fixation. Clin Orthop 1989; 241: 2435.
  • 6
    Cheal EJ, Mansmann KA, DiGioia AMd, Hayes WC, Perren SM. Role of interfragmentary strain in fracture healing: ovine model of a healing osteotomy. J Orthop Res 1991; 9: 13142.
  • 7
    Claes L. Measuring bone healing in osteosynthesis with external fixator using the Fraktometer FM 100. Chirurg 1991; 62: 3545.
  • 8
    Claes L, Augat P, Suger G, Wilke HJ. Influence of size and stability of the osteotomy gap on the success of fracture healing. J Orthop Res 1997; 15: 57784.
  • 9
    Claes L, Wolf S, Augat P. Mechanical modification of callus healing. Chirurg 2000; 71: 98994.
  • 10
    Claes LE, Heigele CA, Neidlinger-Wilke C, Kaspar D, Seidl W, Margevicius KJ, et al. Effects of mechanical factors on the fracture healing process. Clin Orthop 1998; 355(Suppl): 13247.
  • 11
    Draper ER, Strachan RK, Hughes SP, Nicol AC, Paul JP. The design and performance of an experimental external fixator with variable axial stiffness and a compressive force transducer. Med Eng Phys 1997; 19: 6905.
  • 12
    Duda GN, Eckert-Hubner K, Sokiranski R, Kreutner A, Miller R, Claes L. Analysis of inter-fragmentary movement as a function of musculoskeletal loading conditions in sheep. J Biomech 1998; 31: 20110.
  • 13
    Duda GN, Kirchner H, Wilke HJ, Claes L. A method to determine the 3-D stiffness of fracture fixation devices and its application to predict inter-fragmentary movement. J Biomech 1998; 31: 24752.
  • 14
    Duda GN, Mandruzzato F, Heller M, Goldhahn J, Moser R, Hehli M, et al. Mechanical boundary conditions of fracture healing: borderline indications in the treatment of unreamed tibial nailing. J Biomech 2001; 34: 63950.
  • 15
    Duda GN, Sollmann M, Sporrer S, Hoffmann JE, Kassi JP, Khodadadyan C, et al. Interfragmentary motion in tibial osteotomies stabilized with ring fixators. Clin Orthop 2002; 396: 16372.
  • 16
    Egger EL, Gottsauner-Wolf F, Palmer J, Aro HT, Chao EY. Effects of axial dynamization on bone healing. J Trauma 1993; 34: 18592.
  • 17
    Gardner TN, Evans M, Hardy J, Kenwright J. Dynamic interfragmentary motion in fractures during routine patient activity. Clin Orthop 1997; 336: 21625.
  • 18
    Goodship AE. Mechanical stimulus to bone. Ann Rheum Dis 1992; 51: 46.
  • 19
    Goodship AE, Watkins PE, Rigby HS, Kenwright J. The role of fixator frame stiffness in the control of fracture healing. An experimental study. J Biomech 1993; 26: 102735.
  • 20
    Goodship AE, Cunningham JL, Kenwright J. Strain rate and timing of stimulation in mechanical modulation of fracture healing. Clin Orthop 1998; 355(Suppl): 10515.
  • 21
    Hente R, Cordey J, Rahn BA, Maghsudi M, von Gumppenberg S, Perren SM. Fracture healing of the sheep tibia treated using a unilateral external fixator. Comparison of static and dynamic fixation. Injury 1999; 30(Suppl 1): A4451.
  • 22
    Kassi JP, Hoffmann JE, Heller M, Raschke M, Duda GN. Assessment of the stability of fracture fixation systems: mechanical device to investigate the 3-D stiffness in vitro. Biomed Tech (Berl) 2001; 46: 24752.
  • 23
    Klein P, Schell H, Streitparth F, Bail H, Kandziora F, Bragulla H, et al. Mounting plane of external fixators influences callus tissue formation. Trans Orthop Res Soc, Dallas 2002: 715.
  • 24
    Le AX, Miclau T, Hu D, Helms JA. Molecular aspects of healing in stabilized and non-stabilized fractures. J Orthop Res 2001; 19: 7884.
  • 25
    Miclau T, Thompson Z, Colnot C, Huang S, Werb Z, Helms JA. The effect of early stability on fracture repair. Trans Orthop Res Soc, Dallas 2002: 0709.
  • 26
    Nomura S, Takano-Yamamoto T. Molecular events caused by mechanical stress in bone. Matrix Biol 2000; 19: 916.
  • 27
    Park SHKOC, McKellop H, Sarmiento A. The influence of active shear or compressive motion on fracture-healing. J Bone Joint Surg Am 1998; 80: 86878.
  • 28
    Probst A, Spiegel HU. Cellular mechanisms of bone repair. J Invest Surg 1997; 10: 7786.
  • 29
    Rosenbaum D, Becker HP. Plantar pressure distribution measurements. Technical background and clinical applications. Foot Ankle Surg 1997; 3: 114.
  • 30
    Sarmiento A, Schaeffer JF, Beckerman L, Latta LL, Enis JE. Fracture healing in rat femora as affected by functional weight-bearing. J Bone Joint Surg Am 1977; 59: 36975.
  • 31
    Sarmiento A, McKellop HA, Llinas A, Park SH, Lu B, Stetson W, et al. Effect of loading and fracture motions on diaphyseal tibial fractures. J Orthop Res 1996; 14: 804.
  • 32
    Stürmer KM. Histologic finding of fracture healing using external fixation and its clinical significance. Unfallchirurgie 1984; 10: 11022.
  • 33
    Wallace AL, Draper ER, Strachan RK, McCarthy ID, Hughes SP. The vascular response to fracture micromovement. Clin Orthop 1994; 301: 28190.
  • 34
    Wang N, Butler JP, Ingber DE. Mechanotransduction across the cell surface and through the cytoskeleton. Science 1993; 260: 11247.
  • 35
    Wolf S, Janousek A, Pfeil J, Veith W, Haas F, Duda G, et al. The effects of external mechanical stimulation on the healing of diaphyseal osteotomies fixed by flexible external fixation. Clin Biomech (Bristol, Avon) 1998; 13: 35964.
  • 36
    Wu JJ, Shyr HS, Chao EY, Kelly PJ. Comparison of osteotomy healing under external fixation devices with different stiffness characteristics. J Bone Joint Surg Am 1984; 66: 125864.
  • 37
    Yamagishi M, Yoshimura Y. The biomechanics of fracture healing. J Bone Joint Surg 1955; 37-A: 103568.