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References

  • 1
    Altman RD, Latta LL, Keer R, et al. Effect of nonsteroidal antiinflammatory drugs on fracture healing: a laboratory study in rats. J Orthop Trauma 1995; 9: 392400.
  • 2
    Anderson DM, Maraskovsky E, Billingsley WL, et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 1997; 390: 1759.
  • 3
    Bekker PJ, Holloway D, Nakanishi A, et al. The effect of a single dose of osteoprotegerin in postmenopausal women. J Bone Miner Res 2001; 16: 34860.
  • 4
    Bonnarens F, Einhorn TA. Production of a standard closed fracture in laboratory animal bone. J Orthop Res 1984; 2: 97101.
  • 5
    Buckwalter JA, Einhorn TA, Bolander ME, Crue RL. Healing of the musculoskeletal tissues. In: RockwoodJrCA, GreenDP, editors. Fractures in Adults. Philadelphia: Lippincott-Raven: 2001.
  • 6
    Burgess TL, Qian Y, Kaufman S, et al. The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts. J Cell Biol 1999; 145: 52738.
  • 7
    Capparelli C, Kostenuik PJ, Morony S, et al. Osteoprotegerin prevents and reverses hypercalcemia in a murine model of humoral hypercalcemia of malignancy. Cancer Res 2000; 60: 7837.
  • 8
    Childs LM, Paschalis EP, Xing L, et al. In vivo RANK signaling blockade using the receptor activator of NF-kappaB:Fc effectively prevents and ameliorates wear debris-induced osteolysis via osteoclast depletion without inhibiting osteogenesis. J Bone Miner Res 2002; 17: 1929.
  • 9
    Cruess RL, Dumont J. Fracture healing. Can J Surg 1975; 18: 40313.
  • 10
    Dougall WC, Glaccum M, Charrier K, et al. RANK is essential for osteoclast and lymph node development. Genes Dev 1999; 13: 241224.
  • 11
    Einhorn TA. The cell and molecular biology of fracture healing. Clin Orthop 1998; (Suppl): S721.
  • 12
    Giannoudis PV, MacDonald DA, Matthews SJ, et al. The influence of reaming and non-steroidal anti-inflammatory drugs. J Bone Joint Surg Br 2000; 82: 6558.
  • 13
    Harris WH, Heaney RP. Skeletal renewal and metabolic bone disease. N Engl J Med 1969; 280: 2539, contd.
  • 14
    Hiltunen A, Vuorio E, Aro HT. A standardized experimental fracture in the mouse tibia. J Orthop Res 1993; 11: 30512.
  • 15
    Hofbauer LC, Khosla S, Dunstan CR, et al. The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption. J Bone Miner Res 2000; 15: 212.
  • 16
    Honore P, Luger NM, Sabino MA, et al. Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord. Nat Med 2000; 6: 5218.
  • 17
    Hsu H, Lacey DL, Dunstan CR, et al. Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc Nat Acad Sci USA 1999; 96: 35405.
  • 18
    Jimi E, Akiyama S, Tsurukai T, et al. Osteoclast differentiation factor acts as a multifunctional regulator in murine osteoclast differentiation and function. J Immunol 1999; 163: 43442.
  • 19
    Kim N, Odgren PR, Kim DK, et al. Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene. Proc Nat Acad Sci USA 2000; 97: 1090510.
  • 20
    Kon T, Cho TJ, Aizawa T, et al. Expression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing. J Bone Miner Res 2001; 16: 100414.
  • 21
    Kong YY, Feige U, Sarosi I, et al. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature 1999; 402: 3049.
  • 22
    Kong YY, Yoshida H, Sarosi I, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999; 397: 31523.
  • 23
    Lacey DL, Timms E, Tan HL, et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998; 93: 16576.
  • 24
    Li J, Mori S, Kaji Y, et al. Effect of bisphosphonate (incadronate) on fracture healing of long bones in rats. J Bone Miner Res 1999; 14: 96979.
  • 25
    Li J, Mori S, Kaji Y, et al. Concentration of bisphosphonate (incadronate) in callus area and its effects on fracture healing in rats. J Bone Miner Res 2000; 15: 204251.
  • 26
    Li J, Sarosi I, Yan XQ, et al. RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. Proc Nat Acad Sci USA 2000; 97: 156671.
  • 27
    Marks Jr SC, Lane PW. Osteopetrosis, a new recessive skeletal mutation on chromosome 12 of the mouse. J Hered 1976; 67: 118.
  • 28
    Oyajobi BO, Anderson DM, Traianedes K, et al. Therapeutic efficacy of a soluble receptor activator of nuclear factor kappaB-IgG Fc fusion protein in suppressing bone resorption and hypercalcemia in a model of humoral hypercalcemia of malignancy. Cancer Res 2001; 61: 25728.
  • 29
    Peter CP, Cook WO, Nunamaker DM, et al. Effect of alendronate on fracture healing and bone remodeling in dogs. J Orthop Res 1996; 14: 749.
  • 30
    Schwarz EM, O'Keefe RJ. Breakthrough in bone: the molecular mechanism of osteoclast/osteoblast coupling revealed. Curr Opin Orthop 2000; 11: 32935.
  • 31
    Simonet WS, Lacey DL, Dunstan CR, et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density [see comments]. Cell 1997; 89: 30919.
  • 32
    Teitelbaum SL. Bone resorption by osteoclasts. Science 2000; 289: 15048.
  • 33
    Vu TH, Shipley JM, Bergers G, et al. MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell 1998; 93: 41122.
  • 34
    Waters RV, Gamradt SC, Asnis P, et al. Systemic corticosteroids inhibit bone healing in a rabbit ulnar osteotomy model. Acta Orthop Scand 2000; 71: 31621.
  • 35
    Yasuda H, Shima N, Nakagawa N, et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Nat Acad Sci USA 1998; 95: 3597602.