Expression and immunohistochemical localization of galectin-3 in various mouse tissues

Authors

  • Heechul Kim,

    1. Department of Veterinary Medicine, Cheju National University, Jeju 690-756, South Korea
    2. Applied Radiological Science Research Institute, Cheju National University, Jeju 690-756, South Korea
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  • Jeeyoung Lee,

    1. Department of Veterinary Medicine, Cheju National University, Jeju 690-756, South Korea
    2. Applied Radiological Science Research Institute, Cheju National University, Jeju 690-756, South Korea
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  • Jin Won Hyun,

    1. Applied Radiological Science Research Institute, Cheju National University, Jeju 690-756, South Korea
    2. Department of Biochemistry, College of Medicine, Cheju National University, Jeju 690-756, South Korea
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  • Jae Woo Park,

    1. Applied Radiological Science Research Institute, Cheju National University, Jeju 690-756, South Korea
    2. Department of Nuclear and Energy Engineering, Cheju National University, Jeju 690-756, South Korea
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  • Hong-gu Joo,

    Corresponding author
    1. Department of Veterinary Medicine, Cheju National University, Jeju 690-756, South Korea
    2. Applied Radiological Science Research Institute, Cheju National University, Jeju 690-756, South Korea
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  • Taekyun Shin

    Corresponding author
    1. Department of Veterinary Medicine, Cheju National University, Jeju 690-756, South Korea
    2. Applied Radiological Science Research Institute, Cheju National University, Jeju 690-756, South Korea
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Corresponding author. Department of Veterinary Medicine, Cheju National University, Jeju 690-756, South Korea. Tel.: +82 64 754 3363; fax: +82 64 756 3354. shint@cheju.ac.kr

Corresponding author. Department of Veterinary Medicine, Cheju National University, Jeju 690-756, South Korea. Tel.: +82 64 754 3379; fax: +82 64 756 3354. jooh@cheju.ac.kr

Abstract

The expression and immunohistochemical localization of galectin-3, a β-galactoside-binding protein, was studied in several mouse tissues. Galectin-3 expression was low in the cerebrum, heart, and pancreas, and moderate in the liver, ileum, kidney, and adrenal gland. High expression of galectin-3 was found in the lung, spleen, stomach, colon, uterus, and ovary. The results of Western blot analysis largely matched the immunohistochemical findings for galectin-3. These findings suggest that galectin-3 is differentially expressed in a variety of organs in the mouse. This study provides valuable information for research on galectin-3.

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