• [1]
    Shah, D.T., Glover, D.D., Larsen, B. (1995) In situ mycotoxin production by Candida albicans in women with vaginitis. Gynecol. Obstet. Invest. 39, 6769.
  • [2]
    Wilhite, S.E., Lumsden, R.D., Straney, D.C. (2001) Peptide synthetase gene in Trichoderma virens. Appl. Environ. Microbiol. 67, 50555062.
  • [3]
    Macdonald, J.C., Slater, G.P. (1975) Biosynthesis of gliotoxin and mycelianamide. Can. J. Biochem. 53, 475478.
  • [4]
    Gardiner, D.M., Waring, P., Howlett, B.J. (2005) The epipolythiodioxopiperazine (ETP) class of fungal toxins: distribution, mode of action, functions and biosynthesis. Microbiol 151, 10211032.
  • [5]
    Munday, R. (1987) Studies on the mechanism of toxicity of the mycotoxin sporidesmin. Generation of hydroxyl radicals by sporidesmin. J. Appl. Toxicol. 7, 1722.
  • [6]
    Chai, C.L.L., Waring, P. (2000) Redox sensitive epidithiodioxopiperazines in biological mechanisms of toxicity. Redox Report 5, 257264.
  • [7]
    Bernardo, P.H., Brasch, N., Chai, C.L., Waring, P. (2003) A novel redox mechanism for the glutathione-dependent reversible uptake of a fungal toxin in cells. J. Biol. Chem. 278, 4654946555.
  • [8]
    Sutton, P., Waring, P., Mullbacher, A. (1996) Exacerbation of invasive aspergillosis by the immunosuppressive fungal metabolite, gliotoxin. Immunol. Cell Biol. 74, 318322.
  • [9]
    Sutton, P., Newcombe, N.R., Waring, P., Mullbacher, A. (1994) In vivo immunosuppressive activity of gliotoxin, a metabolite produced by human pathogenic fungi. Infect. Immun. 62, 11921198.
  • [10]
    Hurne, A.M., Chai, C.L.L., Moerman, K., Waring, P. (2002) Influx of calcium through a redox-sensitive plasma membrane channel in thymocytes causes early necrotic cell death induced by the epipolythiodioxopiperazine toxins. J. Biol. Chem. 277, 3163131638.
  • [11]
    Waring, P., Eichner, R.D., Mullbacher, A., Sjaarda, A. (1988) Gliotoxin induces apoptosis in macrophages unrelated to its antiphagocytic properties. J. Biol. Chem. 263, 1849318499.
  • [12]
    Gardiner, D.M., Cozijnsen, A.J., Wilson, L.M., Pedras, M.S.C., Howlett, B.J. (2004) The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans. Mol. Microbiol. 53, 13071318.
  • [13]
    Gardiner, D.M., Jarvis, R.S., Howlett, B.J. (2005) The ABC transporter gene in the sirodesmin biosynthetic gene cluster of Leptosphaeria maculans is not essential for sirodesmin production but facilitates self-protection. Fungal Genet. Biol. 42, 257263.
  • [14]
    Muller, P.Y., Janovjak, H., Miserez, A.R., Dobbie, Z. (2002) Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechnology 32, 13721379.
  • [15]
    Cambareri, E.B., Jensen, B.C., Schabtach, E., Selker, E.U. (1989) Repeat-induced G–C to A–T mutations in Neurospora. Science 244, 15711575.
  • [16]
    Correia, T., Grammel, N., Ortel, I., Keller, U., Tudzynski, P. (2003) Molecular cloning and analysis of the ergopeptine assembly system in the ergot fungus Claviceps purpurea. Chem. Biol. 10, 12811292.
  • [17]
    Bose, A.K., Das, K.G., Funke, P.T., Kugajevsky, I., Shukla, O.P., Khanchandani, K.S., Suhadolnik, R.J. (1968) Biosynthetic studies on gliotoxin using stable isotopes and mass spectral methods. J. Am. Chem. Soc. 90, 10381041.
  • [18]
    Watanabe, A., Kamei, K., Sekine, T., Waku, M., Nishimura, K., Miyaji, M., Kuriyama, T. (2003) Immunosuppressive substances in Aspergillus fumigatus culture filtrate. J. Infect. Chemother. 9, 114121.
  • [19]
    Kirby, G.W., Robins, D.J. (1980) The biosynthesis of gliotoxin and related epipolythiodioxopiperazines. In: The biosynthesis of mycotoxins (Steyn, P.S., Ed.), pp.301–326 Academic Press, New York.
  • [20]
    Ferezou, J.-P., Quesneau-Thierry, A., Servy, C., Zissmann, E., Barbier, M. (1980) Sirodesmin PL Biosynthesis in Phoma lingam Tode. J. Chem. Soc. Perkin Trans. 1, 17391746.
  • [21]
    dos Santos, V.M., Dorner, J.W., Carreira, F. (2003) Isolation and toxigenicity of Aspergillus fumigatus from moldy silage. Mycopathology 156, 133138.
  • [22]
    Wilhite, S.E., Straney, D.C. (1996) Timing of gliotoxin biosynthesis in the fungal biological control agent Gliocladium virens (Trichoderma virens). Appl. Microbiol. Biotechnol. 45, 513518.
  • [23]
    Brown, D.W., Yu, J.H., Kelkar, H.S., Fernandes, M., Nesbitt, T.C., Keller, N.P., Adams, T.H., Leonard, T.J. (1996) Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans. Proc. Natl. Acad. Sci. USA 93, 14181422.
  • [24]
    Proctor, R.H., Brown, D.W., Plattner, R.D., Desjardins, A.E. (2003) Co-expression of 15 contiguous genes delineates a fumonisin biosynthetic gene cluster in Gibberella moniliformis. Fungal Genet. Biol. 38, 237249.
  • [25]
    Allocco, D.J., Kohane, I.S., Butte, A.J.Quantifying the relationship between co-expression, co-regulation and gene function BMC Bioinform. 5 2004 18
  • [26]
    Ihmels, J., Bergmann, S., Barkai, N. (2004) Defining transcription modules using large-scale gene expression data. Bioinformatics 20, 19932003.
  • [27]
    Oliver, D.J., Nikolau, B., Wurtele, E.S. (2002) Functional genomics: high-throughput mRNA, protein, and metabolite analyses. Metab. Eng. 4, 98106.