First isolation of Streptococcus downei from human dental plaques

Authors

  • So Young Yoo,

    1. Department of Oral Biochemistry, College of Dentistry, Chosun University, 375 Seo-Suk Dong, Dong-Ku, Gwang-ju 501–759, Republic of Korea
    Search for more papers by this author
  • Kwan-Joong Kim,

    1. Department of Orthodontics, College of Dentistry, Chosun University, 375 Seo-Suk Dong, Dong-Ku, Gwang-ju 501–759, Republic of Korea
    Search for more papers by this author
  • Seong-Hoon Lim,

    1. Department of Orthodontics, College of Dentistry, Chosun University, 375 Seo-Suk Dong, Dong-Ku, Gwang-ju 501–759, Republic of Korea
    Search for more papers by this author
  • Kwang-Won Kim,

    1. Department of Orthodontics, College of Dentistry, Chosun University, 375 Seo-Suk Dong, Dong-Ku, Gwang-ju 501–759, Republic of Korea
    Search for more papers by this author
  • Ho-Keel Hwang,

    1. Department of Conservative Dentistry, College of Dentistry, Chosun University, 375 Seo-Suk Dong, Dong-Ku, Gwang-ju 501–759, Republic of Korea
    Search for more papers by this author
  • Byung-Moo Min,

    1. Department of Oral Biochemistry, College of Dentistry, Seoul National University, 28 Yeonkun-Dong, Chongno-Ku, Seoul 110–749, Republic of Korea
    Search for more papers by this author
  • Son-Jin Choe,

    1. Department of Oral Microbiology and Immunology, College of Dentistry, Seoul National University, 28 Yeonkun-Dong, Chongno-Ku, Seoul 110–749, Republic of Korea
    Search for more papers by this author
  • Joong-Ki Kook

    Corresponding author
    1. Department of Oral Biochemistry, College of Dentistry, Chosun University, 375 Seo-Suk Dong, Dong-Ku, Gwang-ju 501–759, Republic of Korea
    Search for more papers by this author

  • Edited by W. Wade

*Corresponding author. Tel.: +82 62 230 6877; fax: +82 62 224 3706., E-mail address: jkkook@chosun.ac.kr

Abstract

In this study, we isolated four bacterial strains grown on mitis-salivarius sucrose bacitracin agar. The strains had similar biochemical characteristics to biotypes I or II of mutans streptococci. The four isolates were identified as Streptococcus downei by 16S rDNA and dextranase gene (dex) sequencing as well as polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) targeting dex. To our knowledge, this is the first report of the isolation and identification of S. downei from dental plaque in humans. The results suggest that S. downei can inhabit the human oral cavity.

Ancillary