• [1]
    Liu, F., Ooi, V.E., Fung, M.C. (1999) Analysis of immunomodulating cytokine mRNAs in the mouse induced by mushroom polysaccharides. Life Sci. 64, 10051011.
  • [2]
    Kim, G.Y., Oh, W.K., Shin, B.C., Shin, Y.I., Park, Y.C., Ahn, S.C., Lee, J.D., Bae, Y.S., Kwak, J.Y., Park, Y.M. (2004) Proteoglycan isolated from Phellinus linteus inhibits tumor growth through mechanisms leading to an activation of CD11c + CD8 + DC and type I helper T cell-dominant immune state. FEBS Lett. 576, 391400.
  • [3]
    Gray, A.M., Flatt, P.R. (1998) Insulin-releasing and insulin-like activity of Agaricus campestris (mushroom). J. Endocrinol. 157, 259266.
  • [4]
    Siva Sundara Kumar, D., Cheung, H.Y., Lau, C.S., Chen, F., Hyde, K.D. (2004) In vitro studies of endophytic fungi from Tripterygium wilfordii with anti-proliferative activity on human peripheral blood mononuclear cells. J. Ethnopharmacol. 94, 295300.
  • [5]
    Kiho, T., Itahashi, S., Sakushima, M., Matsunaga, T., Usui, S., Ukai, S., Mori, H., Sakamoto, H., Ishiguro, Y. (1997) Polysaccharides in fungi. XXXVIII. Anti-diabetic activity and structural feature of a galactomannan elaborated by Pestalotiopsis species. Biol. Pharm. Bull. 20, 118121.
  • [6]
    Akamatsu, S., Watanabe, A., Tamesada, M., Nakamura, R., Hayashi, S., Kodama, D., Kawase, M., Yagi, K. (2004) Hepatoprotective effect of extracts from Lentinus edodes mycelia on dimethylnitrosamine-induced liver injury. Biol. Pharm. Bull. 27, 19571960.
  • [7]
    Prieto, J.M., Recio, M.C., Giner, R.M., Manez, S., Giner-Larza, E.M., Rios, J.L. (2003) Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. J. Pharm. Pharmacol. 55, 12751282.
  • [8]
    Kimura, Y., Kido, T., Takaku, T., Sumiyoshi, M., Baba, K. (2004) Isolation of an anti-angiogenic substance from Agaricus blazei Murill: its antitumor and antimetastatic actions. Cancer Sci. 95, 758764.
  • [9]
    Lee, Y.L., Kim, H.J., Lee, M.S., Kim, J.M., Han, J.S., Hong, E.K., Kwon, M.S., Lee, M.J. (2003) Oral administration of Agaricus blazei (H1 strain) inhibited tumor growth in a sarcoma 180 inoculation model. Exp. Anim. 52, 371375.
  • [10]
    Chiang, H.C., Wu, D.P., Cherng, I.W., Ueng, C.H. (1995) A sesquiterpene lactone, phenyl and biphenyl compounds from Antrodia cinnamomea. Phytochem. 39, 613616.
  • [11]
    Hsiao, G., Shen, M.Y., Lin, K.H., Lan, M.H., Wu, L.Y., Chou, D.S., Lin, C.H., Su, C.H., Sheu, J.R. (2003) Antioxidative and hepatoprotective effects of Antrodia camphorata extract. J. Agric. Food Chem. 51, 33023308.
  • [12]
    Lee, I.H., Huang, R.L., Chen, C.T., Chen, H.C., Hsu, W.C., Lu, M.K. (2002) Antrodia camphorata polysaccharides exhibit anti-hepatitis B virus effects. FEMS Microbiol. Lett. 209, 6367.
  • [13]
    Ho, J.C., Konerding, M.A., Gaumann, A., Groth, M., Liu, W.K. (2004) Fungal polysaccharopeptide inhibits tumor angiogenesis and tumor growth in mice. Life Sci. 75, 13431356.
  • [14]
    Cui, J., Chisti, Y. (2003) Polysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production. Biotechnol. Adv. 21, 109122.
  • [15]
    Fisher, M., Yang, L.X. (2002) Anticancer effects and mechanisms of polysaccharide-K (PSK): implications of cancer immunotherapy. Anticancer Res. 22, 17371754.
  • [16]
    Wang, S.Y., Hsu, M.L., Hsu, H.C., Tzeng, C.H., Lee, S.S., Shiao, M.S., Ho, C.K. (1997) The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes. Int. J. Cancer 70, 699705.
  • [17]
    Muller, A., Rice, P.J., Ensley, H.E., Coogan, P.S., Kalbfleish, J.H., Kelley, J.L., Love, E.J., Portera, C.A., Ha, T., Browder, I.W., Williams, D.L. (1996) Receptor binding and internalization of a water-soluble (1 [RIGHTWARDS ARROW] 3)-β-d-glucan biologic response modifier in two monocyte/macrophage cell lines. J. Immunol. 156, 34183425.
  • [18]
    Vetvicka, V., Thornton, B.P., Ross, G.D. (1996) Soluble beta-glucan polysaccharide binding to the lectin site of neutrophil or natural killer cell complement receptor type 3 (CD11b/CD18) generates a primed state of the receptor capable of mediating cytotoxicity of iC3b-opsonized target cells. J. Clin. Invest. 98, 5061.
  • [19]
    Moers, M.E.C., Jones, D.M., Eakin, P.A., Fallick, A.E., Grifths, H., Larter, S.R. (1993) Carbohydrate diagenesis in hypersaline environments: application of GC-IRMS to the stable isotope analysis of derivatized saccharides from surficial and buried sediments. Org. Geochem. 20, 927933.
  • [20]
    Dogasaki, C., Murakami, H., Nishijima, M., Ohno, N., Yadomae, T., Miyazaki, T. (1994) Biological activity and structural characterization of alkaline-soluble polysaccharides from the kernels of Prunus mume Sieb. et Zacc. Biol. Pharm. Bull. 17, 386390.
  • [21]
    Shen, Y.C., Chou, C.J., Wang, Y.H., Chen, C.F., Chou, Y.C., Lu, M.K. (2004) Anti-inflammatory activity of the extracts from mycelia of Antrodia camphorata cultured with water-soluble fractions from five different Cinnamomum species. FEMS Microbiol. Lett. 231, 137143.
  • [22]
    Zhang, J., Wang, G., Li, H., Zhuang, C., Mizuno, T., Ito, H., Mayuzumi, H., Okamoto, H., Li, J. (1994) Antitumor active protein-containing glycans from the chinese mushroom Songshan Lingzhi, Ganoderma tsugae Mycelium. Biosci. Biotech. Biochem. 58, 12021205.
  • [23]
    Sasaki, T., Takasuka, N. (1976) Further study of the structure of lentinan, an anti-tumor polysaccharide from Lentinus edodes. Carbohydrate Res. 47, 99104.
  • [24]
    Tabata, K., Ito, W., Kojima, T., Kawabata, S., Misaki, A. (1981) Ultrasonic degradation of schizophyllan, an antitumor polysaccharide produced by Schizophyllum commune Fries. Carbohydrate Res. 89, 121135.
  • [25]
    Cheng, J.J., Yang, C.J., Cheng, C.H., Wang, Y.T., Huang, N.K., Lu, M.K. (2005) Characterization and functional study of Antrodia camphorata lipopolysaccharide. J. Agric. Food Chem. 53, 469474.
  • [26]
    Matsubara, K., Xue, C., Zhao, X., Mori, M., Sugawara, T., Hirata, T. (2005) Effects of middle molecular weight fucoidans on in vitro and ex vivo angiogenesis of endothelial cells. Int. J. Mol. Med. 15, 695699.
  • [27]
    Gu, G., Wei, G., Du, Y. (2004) Synthesis of a 6(V)-sulfated mannopentasaccharide analogue related to PI-88. Carbohydrate Res. 339, 11551162.
  • [28]
    Tapon-Bretaudiere, J., Chabut, D., Zierer, M., Matou, S., Helley, D., Bros, A., Mourao, P.A., Fischer, A.M. (2002) A fucosylated chondroitin sulfate from echinoderm modulates in vitro fibroblast growth factor 2-dependent angiogenesis. Mol. Cancer Res. 1, 96102.
  • [29]
    Giatromanolaki, A., Koukourakis, M., O'Byrne, K., Fox, S., Whitehouse, R., Talbot, D.C., Harris, A.L., Gatter, K.C. (1996) Prognostic value of angiogenesis in operable non-small cell lung cancer. J. Pathol. 179, 8088.
  • [30]
    Giatromanolaki, A., Sivridis, E., Koukourakis, M.I., Georgoulias, V., Gatter, K.C., Harris, A.L. (1999) Intratumoral angiogenesis: a new prognostic indicator for stage I endometrial adenocarcinomas. Oncol. Res. 11, 205212.
  • [31]
    Koukourakis, M.I., Giatromanolaki, A., Fountzilas, G., Sivridis, E., Gatter, K.C., Harris, A.L. (2000) Angiogenesis, thymidine phosphorylase, and resistance of squamous cell head and neck cancer to cytotoxic and radiation therapy. Clin. Cancer Res. 6, 381389.
  • [32]
    Ziche, M., Donnini, S., Morbidelli, L. (2004) Development of new drugs in angiogenesis. Curr. Drug Targets 5, 485493.
  • [33]
    Shono, T., Ono, M., Izumi, H., Jimi, S.I., Matsushima, K., Okamoto, T., Kohno, K., Kuwano, M. (1996) Involvement of the transcription factor NF-kappaB in tubular morphogenesis of human microvascular endothelial cells by oxidative stress. Mol. Cell Biol. 16, 42314239.
  • [34]
    Hseu, Y.C., Chang, W.C., Hseu, Y.T., Lee, C.Y., Yech, Y.J., Chen, P.C., Chen, J.Y., Yang, H.L. (2002) Protection of oxidative damage by aqueous extract from Antrodia camphorata mycelia in normal human erythrocytes. Life Sci. 71, 469482.
  • [35]
    Cheng, J.J., Huang, N.K., Chang, T.T., Ling Wang, D., Lu, M.K. (2005) Study for anti-angiogenic activities of polysaccharides isolated from Antrodia cinnamomea in endothelial cells. Life Sci. 76, 30293042.
  • [36]
    Fujimiya, Y., Suzuki, Y., Katakura, R., Ebina, T. (1999) Tumor-specific cytocidal and immunopotentiating effects of relatively low molecular weight products derived from the basidiomycete, Agaricus blazei Murill. Anticancer Res. 19, 113118.
  • [37]
    Fujimiya, Y., Suzuki, Y., Oshiman, K., Kobori, H., Moriguchi, K., Nakashima, H., Matumoto, Y., Takahara, S., Ebina, T., Katakura, R. (1998) Selective tumoricidal effect of soluble proteoglucan extracted from the basidiomycete, Agaricus blazei Murill, mediated via natural killer cell activation and apoptosis. Cancer Immunol. Immunother. 46, 147159.
  • [38]
    Mizuno, M., Minato, K., Ito, H., Kawade, M., Terai, H., Tsuchida, H. (1999) Anti-tumor polysaccharide from the mycelium of liquid-cultured Agaricus blazei mill. Biochem. Mol. Biol. Int. 47, 707714.
  • [39]
    Pinheiro, F., Faria, R.R., de Camargo, J.L., Spinardi-Barbisan, A.L., da Eira, A.F., Barbisan, L.F. (2003) Chemoprevention of preneoplastic liver foci development by dietary mushroom Agaricus blazei Murrill in the rat. Food Chem. Toxicol. 41, 15431550.
  • [40]
    Lamy, S., Gingras, D., Beliveau, R. (2002) Green tea catechins inhibit vascular endothelial growth factor receptor phosphorylation. Cancer Res. 62, 381385.
  • [41]
    Kubota, Y., Kleinman, H.K., Martin, G.R., Lawley, T.J. (1988) Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures. J. Cell Biol. 107, 15891598.
  • [42]
    Kuzuya, M., Kinsella, J.L. (1994) Reorganization of endothelial cord-like structures on basement membrane complex (Matrigel): involvement of transforming growth factor beta 1. J. Cell Physiol. 161, 267276.
  • [43]
    Pi, X., Yan, C., Berk, B.C. (2004) Big Mitogen-Activated Protein Kinase (BMK1)/ERK5 Protects Endothelial Cells From Apoptosis. Circ. Res. 94, 362369.
  • [44]
    Holle, L., Song, W., Hicks, L., Holle, E., Holmes, L., Wei, Y., Li, J., Wagner, T., Yu, X. (2004) In vitro targeted killing of human endothelial cells by co-incubation of human serum and NGR peptide conjugated human albumin protein bearing alpha (1–3) galactose epitopes. Oncol. Rep. 11, 613616.
  • [45]
    Rak, J., Weitz, J.I. (2003) Heparin and angiogenesis: size mattersl. Arterioscler. Thromb. Vasc. Biol. 23, 19541955.