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Evidence-Based Approaches to Managing Nausea and Vomiting in Early Pregnancy

Authors

  • Tekoa L. King CNM, MPH,

    1. Tekoa L. King, CNM, MPH, FACNM, is an associate professor in the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California at San Francisco, San Francisco, CA, and is Deputy Editor of the Journal of Midwifery & Women's Health.
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  • Patricia Aikins Murphy CNM, DrPH

    Corresponding author
    1. Patricia Aikins Murphy, CNM, DrPH, FACNM, is a professor and holds the Annette Poulson Cumming Presidential Endowed Chair in Women's and Reproductive Health at the University of Utah College of Nursing, Salt Lake City, UT, and is Deputy Editor of the Journal of Midwifery & Women's Health.
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FACNM, University of Utah College of Nursing, 10 S. 2000 E., Salt Lake City, UT 84112-5880. E-mail: Patricia.murphy@nurs.utah.edu; pmurphy@acnm.org

Abstract

Nausea and vomiting in pregnancy is a continuum that ranges from mild discomfort to significant morbidity. Systematic assessment with the use of the Pregnancy-Unique Quantification of Emesis/Nausea (PUQE) index and timely treatment using evidence-based protocols can decrease the time that many women spend using treatment recommendations that are inadequate. This article reviews the epidemiology of nausea and vomiting in pregnancy, use of the PUQE index, and the evidence for specific nonpharmacologic and pharmacologic treatment regimens. A protocol for clinical management is presented.

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