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  1. 1
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  2. 2
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  3. 3
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  4. 4
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  5. 5
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  6. 6
    Allison G McAtee, Neil Templeton, Jamey D Young, Role of Chinese hamster ovary central carbon metabolism in controlling the quality of secreted biotherapeutic proteins, Pharmaceutical Bioprocessing, 2014, 2, 1, 63

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  7. 7
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  8. 8
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  9. 9
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  10. 10
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  11. 11
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  12. 12
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  13. 13
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  14. 14
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  15. 15
    Woo Suk Ahn, Maciek R. Antoniewicz, Towards dynamic metabolic flux analysis in CHO cell cultures, Biotechnology Journal, 2012, 7, 1
  16. 16
    Yashas Rajendra, Divor Kiseljak, Lucia Baldi, David L Hacker, Florian M Wurm, Influence of glutamine on transient and stable recombinant protein production in CHO and HEK-293 cells, BMC Proceedings, 2011, 5, Suppl 8, P35

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  17. 17
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  18. 18
    Juan A. Hernández Bort, Beate Stern, Nicole Borth, CHO-K1 host cells adapted to growth in glutamine-free medium by FACS-assisted evolution, Biotechnology Journal, 2010, 5, 10
  19. 19
    Alison J. Porter, Alan J. Dickson, Andrew J. Racher, Strategies for selecting Recombinant CHO cell lines for cGMP manufacturing: Realizing the potential in bioreactors, Biotechnology Progress, 2010, 26, 5
  20. 20
    Jong Kwang Hong, Sung Min Cho, Sung Kwan Yoon, Substitution of glutamine by glutamate enhances production and galactosylation of recombinant IgG in Chinese hamster ovary cells, Applied Microbiology and Biotechnology, 2010, 88, 4, 869

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  21. You have free access to this content21
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  22. 22
    Liang Zhao, Li Fan, Jiaqi Wang, Hongxing Niu, Wen-Song Tan, Responses of GS-NS0 Myeloma cells to osmolality: Cell growth, intracellular mass metabolism, energy metabolism, and antibody production, Biotechnology and Bioprocess Engineering, 2009, 14, 5, 625

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  23. 23
    Peifeng Chen, Sarah W. Harcum, Differential display identifies genes in chinese hamster ovary cells sensitive to elevated ammonium, Applied Biochemistry and Biotechnology, 2007, 141, 2-3, 349

    CrossRef

  24. 24
    Claudia Altamirano, Andres Illanes, Silvana Becerra, Jordi Joan Cairó, Francesc Gòdia, Considerations on the lactate consumption by CHO cells in the presence of galactose, Journal of Biotechnology, 2006, 125, 4, 547

    CrossRef

  25. 25
    Hyoung Jin Kim, Hong-Jin Kim, Glycosylation variant analysis of recombinant human tissue plasminogen activator produced in urea-cycle-enzyme-expressing Chinese hamster ovary (CHO) cell line, Journal of Bioscience and Bioengineering, 2006, 102, 5, 447

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  26. 26
    Frederyk A. Ngantung, Peter G. Miller, Fikile R. Brushett, Goh Lin Tang, Daniel I.C. Wang, RNA interference of sialidase improves glycoprotein sialic acid content consistency, Biotechnology and Bioengineering, 2006, 95, 1
  27. 27
    Peifeng Chen, Sarah W. Harcum, Effects of amino acid additions on ammonium stressed CHO cells, Journal of Biotechnology, 2005, 117, 3, 277

    CrossRef

  28. 28
    C Altamirano, C Paredes, A Illanes, J.J Cairó, F Gòdia, Strategies for fed-batch cultivation of t-PA producing CHO cells: substitution of glucose and glutamine and rational design of culture medium, Journal of Biotechnology, 2004, 110, 2, 171

    CrossRef

  29. 29
    H.J Cruz, C.M Freitas, P.M Alves, J.L Moreira, M.J.T Carrondo, Effects of ammonia and lactate on growth, metabolism, and productivity of BHK cells, Enzyme and Microbial Technology, 2000, 27, 1-2, 43

    CrossRef

  30. 30
    M. Yang, M. Butler, Effects of ammonia on CHO cell growth, erythropoietin production, and glycosylation, Biotechnology and Bioengineering, 2000, 68, 4
  31. 31
    Hyo-Soon Park, Ik-Hwan Kim, Ick-Young Kim, Ki-Ho Kim, Hong-Jin Kim, Expression of carbamoyl phosphate synthetase I and ornithine transcarbamoylase genes in Chinese hamster ovary dhfr-cells decreases accumulation of ammonium ion in culture media, Journal of Biotechnology, 2000, 81, 2-3, 129

    CrossRef

  32. 32
    I. Nadeau, J. Sabatié, M. Koehl, M. Perrier, A. Kamen, Human 293 Cell Metabolism in Low Glutamine-Supplied Culture: Interpretation of Metabolic Changes through Metabolic Flux Analysis, Metabolic Engineering, 2000, 2, 4, 277

    CrossRef

  33. 33
    Arindom Sen, Leo A. Behie, The development of a medium for the in vitro expansion of mammalian neural stem cells, The Canadian Journal of Chemical Engineering, 1999, 77, 5
  34. 34
    Hendrik P. J. Bonarius, José H. M. Houtman, Cornelis D. de Gooijer, Johannes Tramper, Georg Schmid, Activity of glutamate dehydrogenase is increased in ammonia-stressed hybridoma cells, Biotechnology and Bioengineering, 1998, 57, 4
  35. 35
    Jörg Neermann, Roland Wagner, Comparative analysis of glucose and glutamine metabolism in transformed mammalian cell lines, insect and primary liver cells, Journal of Cellular Physiology, 1996, 166, 1
  36. 36
    Dana C. Andersen, Charles F. Goochee, The effect of ammonia on the O-linked glycosylation of granulocyte colony-stimulating factor produced by chinese hamster ovary cells, Biotechnology and Bioengineering, 1995, 47, 1