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References and Notes

  • 1
    DiMasi, J. A.; Hansen, R. W.; Grabowski, H. G. The Price of Innovation: New Estimates of Drug Development Costs. J. Health Econ. 2003, 22 (2), 151185.
  • 2
    Cramer, S. M.; Rege, K.; Dordick, J. High Throughtput Screening of Potential Displacer Molecules; Rensselaer Polytechnic Institute: Troy, NY, 2001.
  • 3
    Bensch, M., et al. High Throughput Screening of Chromatographic Phases for Rapid Process Development. Chem. Eng. Technol. 2005, 28 (11), 12741284.
  • 4
    Charlton, H., et al. Chromatography Process Development Using 96 -Well Microplate Formats. BioPharm Int. 2006, June 2.
  • 5
    Thiemann, J.; Jankowski, J.; Rykl, J.; Kurzawski, S.; Pohl, T.; Wittmann-Lievold, B.; Schluter, H. Principle and applications of the protein-purification-parameter screening system. J. Chromatogr. A, 2004, 1043 (1), 7380.
  • 6
    Rege, K; Pepsin, M.; Falcon. B.; Steele, L.; Heng. M. High-throughput process development for recombinant protein purification. Biotechnol. Bioeng. 2006, 93 (4), 618630.
  • 7
    Linden, T. Untersuchungen zum inneren Transport bei der Proteinadsorption an poröse Medien mittels konfokaler Laser-Rester-Mikroskopie. Heinrich-Heine University: Dusseldorf, 2001; p 227.
  • 8
    Coffman, J. L.; Kelly, B.; Kramarczyk, J. High Throughput Screening of Resins and Excipients for Optimization of Selectivity. Recovery of Biological Products X I, Banff, Alberta, Canada, 2003.
  • 9
    Kramarczyk, J. High Throughput Screening of chromatogrpahic resins and Excipients for optimizing selectivity. Biotechnology Engineering; Tufts University: Medford, MA, 2003.
  • 10
    Arve, B. H.; Liapis, A. I. Modelling and Analysis of Biospecific Adsorption in a Finite Bath. AIChE J. 1987, 33 (2), 179193.
  • 11
    Chase H. A. Predictionof the Performanc of Preparative Affinity Chromatography. J. Chromatogr. 1984, 297, 179202.
  • 12
    Hunter, A. K.; Carta, G. Protein Adsorption on Novel Acrylamido-Based Polymeric Ion Exchangers: II. Adsorption Rates and Column Behavior. J. Chromatogr. A 2000, 897(1–2), 8197.
  • 13
    Wesselingh, J. A.; Bosma, J. C. Protein Ion-Exchange Adsorption Kinetics. AIChE J. 2001, 47 (7), 15711580.
  • 14
    Lewus, R. K.; Carta, G. Binary Protein Adsorption on Gel-Composite Ion-Exchange Media. AIChE J. 1999, 45 (3), 512522.
  • 15
    Sofer, G.; Hagel, L.; Jagschies, G. Handbook of Process Chromatography: A Guide to Optimization, Scale-Up and Validation, 2nd ed.; Academic Press: New York, 2007.
  • 16
    Giddings, J. C. Dynamics of Chromatography: Part 1 Principles and Theory. Keller, J. C. G. R. A., Ed.; Marcel Dekker, Inc.: New York, 1965; Vol. 1.
  • 17
    Helfferich F. G. Modelsand Physical Reality in Ion-Exchange Kinetics. React. Polym. 1990, 13, 191194.
  • 18
    Carta, G.; Ubiera, A. R.; Pabst, T. M. Protein Mass Transfer Kinetics in Ion Exchange Media: Measurements and Interpretations. Chem. Eng. Technol. 2005, 28 (11), 12521264.
  • 19
    Stickel, J. J.; Fotopoulos, A. Pressure-Flow Relationships for Packed Beds of Compressible Chromatography Media at Laboratory and Production Scale. Biotechnol. Prog. 2001, 17 (4), 744751.
  • 20
    Öberg, K., et al. High Throughput Process Development: Determination of Dynamic Binding Capacity Using a Microtiter Plate Format. Poster presentation at the SBE Conference on Accelerating Biopharmaceutical Development, San Diego, CA, 2007.