Biotechnology Progress

Cover image for Vol. 31 Issue 6

November/December 2015

Volume 31, Issue 6

Pages i–iv, 1443–1719

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Biocatalysts and Bioreactor Design
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      Issue Information (pages i–iv)

      Article first published online: 21 DEC 2015 | DOI: 10.1002/btpr.1976

  2. Bioseparations and Downstream Processing

    1. Top of page
    2. Issue Information
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Biocatalysts and Bioreactor Design
  3. Applied Cellular Physiology and Metabolic Engineering

    1. Top of page
    2. Issue Information
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Biocatalysts and Bioreactor Design
    1. Comparison of bacterial diversity in full scale anammox bioreactors operated under different conditions (pages 1464–1472)

      Alejandro Gonzalez-Martinez, Francisco Osorio, Jose A. Morillo, Alejandro Rodriguez-Sanchez, Jesus Gonzalez-Lopez, Ben A. Abbas and Mark C. M. van Loosdrecht

      Article first published online: 25 AUG 2015 | DOI: 10.1002/btpr.2151

  4. Biocatalysts and Bioreactor Design

    1. Top of page
    2. Issue Information
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Biocatalysts and Bioreactor Design
    1. Chemostat production of pediocin SM-1 by Pediococcus pentosaceus Mees 1934 (pages 1481–1486)

      Maria Papagianni and Daniel Sergelidis

      Article first published online: 5 OCT 2015 | DOI: 10.1002/btpr.2171

    2. Binding domains of Bacillus anthracis phage endolysins recognize cell culture age-related features on the bacterial surface (pages 1487–1493)

      Elena E. Paskaleva, Ruchir V. Mundra, Krunal K. Mehta, Ravindra C. Pangule, Xia Wu, Willing S. Glatfelter, Zijing Chen, Jonathan S. Dordick and Ravi S. Kane

      Article first published online: 13 OCT 2015 | DOI: 10.1002/btpr.2172

  5. Bioseparations and Downstream Processing

    1. Top of page
    2. Issue Information
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Biocatalysts and Bioreactor Design
    1. Production of lignosulfonate in NSSC-based biorefinery (pages 1508–1514)

      Dmitry Tarasov, Mathew Leitch and Pedram Fatehi

      Article first published online: 19 AUG 2015 | DOI: 10.1002/btpr.2149

    2. Caprylic acid-induced impurity precipitation from protein A capture column elution pool to enable a two-chromatography-step process for monoclonal antibody purification (pages 1515–1525)

      Ji Zheng, Lu Wang, Barbara Twarowska, Sarah Laino, Colleen Sparks, Timothy Smith, Reb Russell and Michelle Wang

      Article first published online: 4 SEP 2015 | DOI: 10.1002/btpr.2154

    3. Robust depth filter sizing for centrate clarification (pages 1542–1550)

      Herb Lutz, Kate Chefer, Michael Felo, Benjamin Cacace, Sarah Hove, Bin Wang, Mark Blanchard, George Oulundsen, Rob Piper and Xiaoyang Zhao

      Article first published online: 8 DEC 2015 | DOI: 10.1002/btpr.2188

    4. Accelerating sample preparation through enzyme-assisted microfiltration of Salmonella in chicken extract (pages 1551–1562)

      Hunter B. Vibbert, Seockmo Ku, Xuan Li, Xingya Liu, Eduardo Ximenes, Thomas Kreke, Michael R. Ladisch, Amanda J. Deering and Andrew G. Gehring

      Article first published online: 7 OCT 2015 | DOI: 10.1002/btpr.2167

    5. Efficient preparation and site-directed immobilization of VHH antibodies by genetic fusion of poly(methylmethacrylate)-binding peptide (PMMA-Tag) (pages 1563–1570)

      Yoichi Kumada, Bongmun Kang, Kagenari Yamakawa, Michimasa Kishimoto and Jun-Ichi Horiuchi

      Article first published online: 19 OCT 2015 | DOI: 10.1002/btpr.2169

  6. Cell Culture and Tissue Engineering

    1. Top of page
    2. Issue Information
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Biocatalysts and Bioreactor Design
    1. Enhanced plasmid DNA utilization in transiently transfected CHO–DG44 cells in the presence of polar solvents (pages 1571–1578)

      Yashas Rajendra, Sowmya Balasubramanian, Divor Kiseljak, Lucia Baldi, Florian M. Wurm and David L. Hacker

      Article first published online: 25 AUG 2015 | DOI: 10.1002/btpr.2152

    2. An EBV-based plasmid can replicate and maintain in stem cells (pages 1579–1585)

      Seyed Mohammad Ali Hosseini Rad, Taravat Bamdad, Ehsan Arefian, Majid Mossahebi-Mohammadi and Majid Sadeghizadeh

      Article first published online: 25 AUG 2015 | DOI: 10.1002/btpr.2153

    3. Fermentanomics: Relating quality attributes of a monoclonal antibody to cell culture process variables and raw materials using multivariate data analysis (pages 1586–1599)

      Anurag S. Rathore, Sumit Kumar Singh, Mili Pathak, Erik K. Read, Kurt A. Brorson, Cyrus D. Agarabi and Mansoor Khan

      Article first published online: 31 AUG 2015 | DOI: 10.1002/btpr.2155

    4. Production of oncolytic adenovirus and human mesenchymal stem cells in a single-use, Vertical-Wheel bioreactor system: Impact of bioreactor design on performance of microcarrier-based cell culture processes (pages 1600–1612)

      Marcos F. Q. Sousa, Marta M. Silva, Daniel Giroux, Yas Hashimura, Robin Wesselschmidt, Brian Lee, António Roldão, Manuel J. T. Carrondo, Paula M. Alves and Margarida Serra

      Article first published online: 4 SEP 2015 | DOI: 10.1002/btpr.2158

    5. Morphological and functional characterization of human induced pluripotent stem cell-derived neurons (iCell Neurons) in defined culture systems (pages 1613–1622)

      Bonnie J. Berry, Nesar Akanda, Alec S.T. Smith, Christopher J. Long, Mark T. Schnepper, Xiufang Guo and James J. Hickman

      Article first published online: 11 SEP 2015 | DOI: 10.1002/btpr.2160

    6. Application of high-throughput mini-bioreactor system for systematic scale-down modeling, process characterization, and control strategy development (pages 1623–1632)

      Vijay Janakiraman, Chris Kwiatkowski, Rashmi Kshirsagar, Thomas Ryll and Yao-Ming Huang

      Article first published online: 28 SEP 2015 | DOI: 10.1002/btpr.2162

    7. Fingerprint detection and process prediction by multivariate analysis of fed-batch monoclonal antibody cell culture data (pages 1633–1644)

      Michael Sokolov, Miroslav Soos, Benjamin Neunstoecklin, Massimo Morbidelli, Alessandro Butté, Riccardo Leardi, Thomas Solacroup, Matthieu Stettler and Hervé Broly

      Article first published online: 7 OCT 2015 | DOI: 10.1002/btpr.2174

    8. Recombinase-mediated cassette exchange (RMCE) for monoclonal antibody expression in the commercially relevant CHOK1SV cell line (pages 1645–1656)

      Lin Zhang, Mara C. Inniss, Shu Han, Mark Moffat, Heather Jones, Baohong Zhang, Wendy L. Cox, James R. Rance and Robert J. Young

      Article first published online: 13 OCT 2015 | DOI: 10.1002/btpr.2175

    9. Combining mechanistic and data-driven approaches to gain process knowledge on the control of the metabolic shift to lactate uptake in a fed-batch CHO process (pages 1657–1668)

      Dénes Zalai, Krisztina Koczka, László Párta, Patrick Wechselberger, Tobias Klein and Christoph Herwig

      Article first published online: 15 OCT 2015 | DOI: 10.1002/btpr.2179

  7. Formulation and Engineering of Biomaterials

    1. Top of page
    2. Issue Information
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Biocatalysts and Bioreactor Design
    1. Production of 2,3-butanediol by Klebsiella oxytoca from various sugars in microalgal hydrolysate (pages 1669–1675)

      Yong Jae Kim, Hyun Woo Joo, Juyi Park, Duk-Ki Kim, Ki Jun Jeong and Yong Keun Chang

      Article first published online: 25 NOV 2015 | DOI: 10.1002/btpr.2168

    2. Size-dependent interaction of cells and hemoglobin–albumin based oxygen carriers prepared using the SPG membrane emulsification technique (pages 1676–1684)

      Yao-Tong Lai, Seiichi Ohta, Kazuki Akamatsu, Shin-ichi Nakao, Yasuyuki Sakai and Taichi Ito

      Article first published online: 9 OCT 2015 | DOI: 10.1002/btpr.2170

  8. Process Sensing and Control

    1. Top of page
    2. Issue Information
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Biocatalysts and Bioreactor Design
    1. Use of random forest in FTIR analysis of LDL cholesterol and tri-glycerides for hyperlipidemia (pages 1693–1702)

      Hua-Zhou Chen, Guo-Qiang Tang, Wu Ai, Li-Li Xu and Ken Cai

      Article first published online: 21 SEP 2015 | DOI: 10.1002/btpr.2161

  9. Biocatalysts and Bioreactor Design

    1. Top of page
    2. Issue Information
    3. Bioseparations and Downstream Processing
    4. Applied Cellular Physiology and Metabolic Engineering
    5. Biocatalysts and Bioreactor Design
    6. Bioseparations and Downstream Processing
    7. Cell Culture and Tissue Engineering
    8. Formulation and Engineering of Biomaterials
    9. Process Sensing and Control
    10. Biocatalysts and Bioreactor Design
    1. Creating a completely “cell-free” system for protein synthesis (pages 1716–1719)

      Mark Thomas Smith, Anthony M. Bennett, Jeremy M. Hunt and Bradley C. Bundy

      Article first published online: 28 AUG 2015 | DOI: 10.1002/btpr.2157

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