Measurements of the tracer radionuclides 129I and 137Cs were conducted on seawater samples collected during the Scientific Ice Expedition cruises to the Arctic Ocean of the U.S. Navy nuclear submarines, USS Cavalla and USS Pogy in 1995 and 1996, respectively. These radionuclides are derived mainly from discharges from the Sellafield (England, United Kingdom) and La Hague (France) nuclear fuel reprocessing plants and are subsequently transported with Atlantic water into the Arctic Ocean through Fram Strait and the Barents Sea. Iodine 129 results from halocline waters (water depths of 59 and 134 m) collected virtually synoptically throughout the central Arctic Ocean during the USS Cavalla cruise clearly show the front between Atlantic origin water having high 129I levels (>100×107 atoms L−1) and Pacific origin water labeled mainly by fallout (<5×107 atoms L−1). This front is aligned with the Mendeleyev Ridge and is displaced toward the Canada Basin with increasing water depth. Iodine 129 levels decrease on isohaline surfaces from stations over the continental slope and Mendeleyev Ridge to stations in the interior of the Makarov Basin. These results are consistent with circulation mechanisms in which the interior of the Makarov Basin is ventilated by lateral mixing from topographically steered boundary currents. Low 129I levels (<2×107 atoms L−1) measured in Atlantic and intermediate water in the northern Canada Basin and over the Alpha Ridge during the USS Pogy cruise indicate that ventilation rates are extremely low in this region. The much higher 129I levels (>30×107 atoms L−1) measured in central regions of the Canada Basin indicate that the interior is more efficiently ventilated than previously thought, possibly by separation from boundary currents flowing over the continental margin north of the Chukchi Plateau. The 129I and 137Cs data were interpreted using a transit time model that provided estimates of 6–7 years (±0.5 years) for the passage of halocline and Atlantic Water from the Norwegian Coastal Current (60°N) to the continental slope of the Makarov Basin and a lower limit of 8 years for transport to interior regions of the Makarov and Amundsen Basins.