Multi-decadal weakening trend of the equatorial Pacific easterly winds since 1960 has reversed after 1993. The trend reversal has induced cooling (shallow thermocline) trend in the equatorial western Pacific before 1993, followed by a warming (deep thermocline) trend from 1993 to the present. All available atmospheric reanalysis products corroborate the trend reversal during the two multi-decadal periods. The magnitudes of the multi-decadal trends of the easterly winds, however, differ among the reanalysis products. The trend reversals of regional ocean circulations are assessed using linear regressions between wind and transport anomalies in an eddy-permitting numerical model, suggesting that since 1993 the Indonesian Throughflow and the Leeuwin Current transports have also reversed their multi-decadal weakening trends.