One of the outstanding issues in space plasma physics is the role of plasma waves and instabilities in the transport of mass, momentum, and energy mediated by plasma flow in space. The large-scale plasma flow in space creates conditions that generate plasma waves at relatively small spatial and temporal scales. The spatial scales of the waves are typically from a few centimeters to a few tens of meters and the corresponding temporal scales are from a few microseconds to less than a second. On the other hand, large-scale plasma flows have scale lengths from a few thousands of kilometers to several Earth radii, and the temporal scales range from about an hour to days. Do the smallscale waves (microprocesses) modify the large-scale flows? Is the modification significant enough to affect the transport of mass, momentum, and energy? And if it is significant enough, how do we incorporate the microprocesses in theoretical models of space plasma flows?