• 1
    Bonifazi F & Bilò MB. Efficacy of specific immunotherapy in allergic asthma: myth or reality? Allergy 1997;52:698 710.
  • 2
    Varney VA, Edwards J, Tabbah K, et al. Clinical efficacy of specific immunotherapy to cat dander: a double-blind placebo-controlled trial. Clin Exp Allergy 1997;27:860 867.
  • 3
    Malling H-J. Immunotherapy as an effective tool in allergy treatment. Allergy 1998;53:461 472.
  • 4
    Rogala B. Risk and safety of immunotherapy. Allergy 1998;53:473 476.
  • 5
    König P & Shaffer J. The effect of drug therapy on long-term outcome of childhood asthma: a possible preview of the international guidelines. J Allergy Clin Immunol 1996;98:1103 1111.
  • 6
    Lemanske RF. A review of the current guidelines for allergic rhinitis and asthma. J Allergy Clin Immunol 1998;101:S392 396.
  • 7
    Van Bever HP & Stevens WJ. Pharmacotherapy of childhood asthma: an inflammatory disease. Drugs 1992;44:36 46.
  • 8
    Osterman K, Carlholm M, Ekelund J, et al. Effect of 1 year daily treatment with 400 μg budesonide (Pulmicort Turbohaler) in newly diagnosed asthmatics. Eur Respir J 1997;10:2210 2215.
  • 9
    Woolcock AJ, Yan K, Salome CM. Effect of therapy on bronchial hyperresponsiveness in the long-term management of asthma. Clin Allergy 1988;18:165 176.
  • 10
    Akdis CA, Blesken T, Akdis M, et al. Peripheral T-cell tolerance in allergen immunotherapy is induced by IL-10 produced by specific T cells, B cells and monocytes [Abstract]. J Allergy Clin Immunol 1998;101:S98.
  • 11
    Durham SR, Schotman E, Jacobson M, et al. Grass pollen immunotherapy (IT): inhibition of allergen induced late skin responses (LPR) is associated with an increase in IL-12 messenger RNA+ cells [Abstract]. J Allergy Clin Immunol 1995;95:304.
  • 12
    Ebner C, Siemann U, Bohle B, et al. Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to allergen and shift from TH2 to TH1 in T-cell clones specific for Phl p 1, a major grass pollen allergen. Clin Exp Allergy 1997;27:1007 1015.
  • 13
    Furin MJ, Norman PS, Creticos PS, et al. Immunotherapy decreases antigen-induced eosinophil cell migration into the nasal cavity. J Allergy Clin Immunol 1991;88:27 32.
  • 14
    Ohashi Y, Nakai Y, Tanaka A, et al. Ten year follow-up study of allergen-specific immunoglobulin E and immunoglobulin G4, soluble interleukin 2 receptor, interleukin 4, soluble intercellular adhesion molecule 1 and soluble vascular cell adhesion molecule 1 in serum of patients on immunotherapy for perennial allergic rhinitis. Scand J Immunol 1998;47:167 178.
  • 15
    Rak S, Björnson A, Håkanson L, Sörenson S, Venge P. The effect of immunotherapy on eosinophil accumulation and production of eosinophil chemotactic activity in the lung of subjects with asthma during natural pollen exposure. J Allergy Clin Immunol 1991;88:878 888.
  • 16
    Van Bever HP, Vereecke IF, Bridts CH, De Clerck LS, Steven WJ. Comparison between the in vitro cytokine production of mononuclear cells of young asthmatics with and without immunotherapy (IT). Clin Exp Allergy 1998;28:943 949.
  • 17
    Calvo M, Marlin F, Grob K, et al. Ten year follow-up in pediatric patients with allergic asthma: evaluation of specific immunotherapy. J Investig Allergol Clin Immunol 1994;4:126 131.
  • 18
    Des Roches A, Paradis L, Knani J, et al. Immunotherapy with a standardized Dermatophagoides pteronyssinus extract. V. Duration of the efficacy of immunotherapy after its cessation. Allergy 1996;51:430 433.
  • 19
    Haugaard L, Dahl R, Sparholt S, Jacobson L. A controlled dose-response study of immunotherapy with standardized extract of house dust mite: long term effect [Abstract]. J Allergy Clin Immunol 1998;101:S58.
  • 20
    Jacobsen L, Nüchel Petersen B, Wihl JÅ, et al. Immunotherapy with partially purified and standardized tree pollen extracts. IV. Results from long-term (6 year) follow-up. Allergy 1997;52:914 920.
  • 21
    Mosbeck HL & Østerballe O. Does the effect of immunotherapy last after termination of treatment? Allergy 1988;43:523 529.
  • 22
    Walker SM, Varney VA, Gaga M, et al. Grass pollen immunotherapy: efficacy and safety during a 4 year follow-up study. Allergy 1995;50:405 413.
  • 23
    Zapletal A, Samanek M, Paul T. Lung function in children and adolescents. Methods, reference values. Progress in Respiratory Research. Vol. 22. Basel: Karger, 1987.
  • 24
    Van Bever HP & Stevens WJ. Effect of hyposensitisation upon the immediate and late asthmatic reaction and upon histamine reactivity in patients allergic to house dust mite (Dermatophagoides pteronyssinus) . Eur Respir J 1992;5:18 22.
  • 25
    Adkinson FN, Eggleston PA, Eney D, et al. A controlled trial of immunotherapy for asthma in allergic children. N Engl J Med 1997;336:324 331.