• 1
    Prescott S, Macaubas C, Holt B, et al. Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T-cell responses towards Th-2 cytokine profile. J Immunol 1998;160:4730 4737.
  • 2
    Kemeny DM, Urbanek R, Ewan P, et al. The subclass of IgG antibody in allergic disease. I. The IgG subclass of antibodies produced following natural exposure to dust mite and grass pollen in atopic and non-atopic individuals. Clin Exp Allergy 1989;19:545 549.
  • 3
    Pène J, Rousset F, Brière F, et al. IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferon γ and α and prostaglandin E2. Proc Natl Acad Sci USA 1988;85:6880 6884.
  • 4
    Ishizaka A, Sakiyama Y, Nakanishi M, et al. The inductive effect of IL-4 on IgG4, and IgE synthesis in human peripheral blood lymphocytes. Clin Exp Immunol 1990;90:392 396.
  • 5
    Kitani A & Strober W. Regulation of Cγ subclass germ-line transcripts in human peripheral blood B cells. J Immunol 1993;151:3478 3488.
  • 6
    Jarrett EEE. Perinatal influences on IgE. Lancet 1984;ii:797.
  • 7
    Dannaeus A, Johansson S, Foucard T. Clinical and immunological aspects of food allergy. II. Development of allergic symptoms and humoral immune response to foods in infants of atopic mothers in the first 24 months of life. Acta Paediatr Scand 1978;67:497 504.
  • 8
    Dannaeus A & Inganäs N. A follow up study of children with food allergy: clinical course in relation to serum IgE and IgG antibodies to milk, egg and fish. Clin Allergy 1981;11:533 539.
  • 9
    Casimir G, Duchateau J, Cuvelier P, Vis H. Maternal immune status against beta-lactoglobulin and cow's milk allergy in the infant. Ann Allergy 1989;63:517 519.
  • 10
    Iikura Y, Akimoto K, Odajima Y, Akazawa A, Nagakura T. How to prevent allergic disease. I. Study of specific IgE, IgG, and IgG4 antibodies in serum of pregnant mothers, cord blood, and infants. Int Arch Allergy Appl Immunol 1989;88:250 252.
  • 11
    Jenmalm M, Holt P, Björkstén B. Maternal influence on IgG subclass antibodies to Bet v 1 during the first 18 months of life as detected with a sensitive ELISA. Int Arch Allergy Immunol 1997;114:175 184.
  • 12
    Holt PG & Macaubas C. Development of long term tolerance versus sensitisation to environmental allergens during the perinatal period. Curr Opin Immunol 1997;9:782 787.
  • 13
    Dreborg S. The skin prick test: methodological studies and clinical applications. Linköping: VTT-Grafiska Vimmerby, 1987.
  • 14
    Dreborg S. The skin prick test in the diagnosis of atopic allergy. J Am Acad Dermatol 1989;21:820 821.
  • 15
    Upham J, Holt B, Baron-Hay M, et al. Inhalant allergen-specific T-cell reactivity is detectable in close to 100% of atopic and normal individuals: covert responses are unmasked by serum-free medium. Clin Exp Allergy 1995;25:634.
  • 16
    Yabuhara A, Macaubas C, Prescott SL, et al. Th-2-polarised immunological memory to inhalant allergens in atopics is established during infancy and early childhood. Clin Exp Allergy 1997;27:1261 1269.
  • 17
    Jefferis R, Reimer C, Skvaril F. Evaluation of monoclonal antibodies having a specificity for human IgG subclasses: results of an IUIS/WHO collaborative study. Immunol Lett 1985;10:223 252.
  • 18
    Warner JA, Miles EA, Jones AC, Quint DJ, Colwell BM, Warner JO. Is deficiency of interferon gamma production by allergen triggered cord blood cells a predictor of atopic eczema? Clin Exp Allergy 1994;24:423 430.
  • 19
    Jeannin P, Delneste Y, Tillien-Leblond I, et al. Abnormal IgG4 antibody response to aeroallergens in allergic patients. Int Arch Allergy Immunol 1994;104:191 198.
  • 20
    Martinez FD. Maternal risk factors in asthma. Ciba Found Symp 1997;206:233 239.
  • 21
    Holt PG, Clough JB, Holt BJ, et al. Genetic “risk” for atopy is associated with delayed postnatal maturation of T-cell competence. Clin Exp Allergy 1992;22:1093 1099.