• 1
    Till S, Durham S, Dickason R, et al. IL-13 production by allergen-stimulated T cells is increased in allergic disease and associated with IL-5 but not IFN-γ expression. Immunology 1997;91:5357.
  • 2
    Li Y, Simons FER, HayGlass KT. Environmental antigen-induced IL-13 responses are elevated among subjects with allergic rhinitis, are independent of IL-4, and are inhibited by endogenous IFN-γ synthesis. J Immunol 1998;161:70077014.
  • 3
    Macaubas C, Sly PD, Burton P, et al. Regulation of T-helper cell responses to inhalant allergen during early child-hood. Clin Exp Allergy 1999;29:12231231.DOI: 10.1046/j.1365-2222.1999.00654.x
  • 4
    Pene J, Rivier A, Lagier B, Becker WM, Michel FB, Bousquet J. Differences in IL-4 release by PBMC are related with heterogeneity of atopy. Immunology 1994;81:5864.
  • 5
    Imada M, Estelle F, Simons R, Jay FT, HayGlass KT. Allergen-stimulated interleukin-4 and interferon-γ production in primary culture: responses of subjects with allergic rhinitis and normal controls. Immunology 1995;85:373380.
  • 6
    Till S, Dickason R, Huston D, et al. IL-5 secretion by allergen-stimulated CD4+ T cells in primary culture: relationship to expression of allergic disease. J Allergy Clin Immunol 1997;99:563569.
  • 7
    Holt PG, Rudin A, Macaubas C, et al. Development of immunologic memory against tetanus toxoid and pertactin antigens from the diphtheria-tetanus-pertussis vaccine in atopic versus nonatopic children. J Allergy Clin Immunol 2000;105:11171122.
  • 8
    Robinson DS, Hamid Q, Ying S, et al. Predominant Th2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med 1992;326:298304.
  • 9
    Vandezande LM, Wallaert B, Desreumaux P, et al. Interleukin-5 immunoreactivity and mRNA expression in gut mucosa from patients with food allergy. Clin Exp Allergy 1999;29:652659.
  • 10
    Del Prete G, Maggi E, Parronchi P, et al. IL-4 is an essential co-factor for the IgE synthesis induced in vitro by human T cell clones and their super-natants. J Immunol 1988;140:41934198.
  • 11
    Punnonen J, Aversa G, Cocks BG, et al. IL-13 induces IL-4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc Natl Acad Sci 1993;90:3730.
  • 12
    Coffman RL & Carty JA. T cell activity that enhances polyclonal IgE production and its inhibition by IFN-γ. J Immunol 1986;136:949954.
  • 13
    Del Prete G, De Carli M, Almerigogna F, Guidizi MG, Biagiotti R, Romagnani S. Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J Immunol 1993;150:353360.
  • 14
    Yabuhara A, Macaubas C, Prescott SL, et al. Th2-polarized immunological memory to inhalant allergens in atopics is established during infancy and early childhood. Clin Exp Allergy 1997;27:12611269.
  • 15
    Tang MLK, Coleman J, Kemp AS. Interleukin-4 and interferon-gamma production in atopic and nonatopic children with asthma. Clin Exp Immunol 1995;25:515521.
  • 16
    Gabrielsson S, Paulie S, Rak S, et al. Specific induction of IL-4 producing cells in response to in vitro allergen stimulation in atopic individuals. Clin Exp Allergy 1997;27:808815.
  • 17
    Rudin A, Johansson E-L, Bergquist C, Holmgren J. Differential kinetics and distribution of antibodies in serum, and nasal and vaginal secretions after nasal and oral vaccination of humans. Infect Immun 1998;66:33903396.
  • 18
    Gagnon R, Akoum A, Hébert J. Lol p-induced IL-4 and IFN-γ production by peripheral blood mononuclear cells of atopic and nonatopic subjects during and out of the pollen season. J Allergy Clin Immunol 1993;91:950956.
  • 19
    Gabrielsson S, Söderlund A, Paulie S, Rak S, Van Der Pouw Kraan TCTM, Troye-Blomberg M. Increased frequencies of allergen-induced interleukin-13-producing cells in atopic individuals during the pollen season. Scand J Immunol 1998;48:429435.DOI: 10.1046/j.1365-3083.1998.00411.x
  • 20
    Crimi E, Gaffi D, Frittoli E, Borgonovo B, Burastero SE. Depletion of circulating allergen-specific Th2 T lymphocytes after allergen exposure in asthma. J Allergy Clin Immunol 1997;99:788797.
  • 21
    Van Der Zee JS, De Groot H, Van Swieten P, Jansen HM, Aalberse RC. Discrepancies between the skin test and IgE antibody assays: study of histamine release, complement activation in vitro, and occurrence of allergen-specific IgG. J Allergy Clin Immunol 1988;82:270281.
  • 22
    Kimura M, Tsuruta S, Yoshida T. IL-4 production by PBMCs on stimulation with mite allergen is correlated with the level of serum IgE antibody against mite in children with bronchial asthma. J Allergy Clin Immunol 2000;105:327332.