Occupational rhinoconjunctivitis and asthma in a wool worker caused by Dermestidae spp.
Article first published online: 11 DEC 2002
Volume 57, Issue 12, pages 1191–1194, December 2002
How to Cite
Brito, F. F., Mur, P., Barber, D., Lombardero, M., Galindo, P. A., Gómez, E. and Borja, J. (2002), Occupational rhinoconjunctivitis and asthma in a wool worker caused by Dermestidae spp. Allergy, 57: 1191–1194. doi: 10.1034/j.1398-9995.2002.23676.x
- Issue published online: 11 DEC 2002
- Article first published online: 11 DEC 2002
- Accepted for publication 8 July 2002
- Coleoptera allergy;
- Dermestidae allergy;
- wool worker allergy;
- occupational asthma
Background: The family Dermestidae belongs to the order Coleoptera. Occupational allergy has been described in museum personnel. A 31-year-old male wool worker presenting rhinoconjunctivitis and asthma episodes probably linked to exposure to Dermestidae-infected wool was investigated.
Methods: Extracts prepared either from insect bodies or from dust from parasitized wool were used for skin prick testing (SPT), conjunctival and bronchial provocation tests and in vitro determinations.
Results: SPT and provocation tests were positive to both extracts. PEFR measurement demonstrated the association between the patient's symptoms and occupational exposure to Dermestidae. Specific IgE to both extracts was detected and immunoblotting revealed several protein bands from 5 to 200 kDa that were reactive to IgE from the patient's serum.
Conclusions: Dermestidae exposure in wool workers when handling parasitized wool can be a cause of IgE-mediated rhinoconjunctivitis and asthma.