• 1
    Holt P. Post-natal maturation of immune competence in infancy and childhood. Pediatr Allergy Immunol 1995;6: 5970.
  • 2
    Prescott S, Macaubas C, Smallacombe T, Holt B, Sly P, Loh R et al. Development of allergen-specific T-cell memory in atopic and normal children. Lancet 1999;353: 196200.
  • 3
    Kondo N, Kobayashi Y, Shinoda S, Kasahara K, Kameyama T, Iwasa S et al. Cord blood lymphocyte responses to food antigens for the prediction of allergic disorders. Arch Dis Child 1992;67: 10031007.
  • 4
    Warner JA, Miles EA, Jones AC, Quint DJ, Colwell BM, Warner JO. Is deficiency of interferon gamma production by allergen triggered cord blood cells a predictor of atopic eczema? Clin Exp Allergy 1994;24: 423430.
  • 5
    Tang MLK, Kemp AS, Thorburn J, Hill D. Reduced interferon gamma secretion in neonates and subsequent atopy. Lancet 1994;344: 983985.
  • 6
    Martinez F, Stern D, Wright A, Holberg C, Taussig L, Halonen M. Association of interleukin-2 and interferon-γ production by blood mononuclear cells in infancy with parental allergy skin tests and with subsequent development of atopy. J Allergy Clin Immunol 1995;96: 652660.
  • 7
    Liao S, Liao T, Chiang B, Huang M, Chen C, Chou C et al. Decreased production of IFN-γ and decreased production of IL-6 by cord blood mononuclear cells of newborns with a high risk of allergy. Clin Exp Allergy 1996;26: 397405.
  • 8
    Kondo N, Kobayashi Y, Shinoda S, Takenaka R, Teramoto T, Kaneko H et al. Reduced interferon gamma production by antigen-stimulated cord blood mononuclear cells is a risk factor of allergic disorders – 6-year follow-up study. Clin Exp Allergy 1998;28: 13401344.
  • 9
    Macaubas C, Sly PD, Burton P, Tiller K, Yabuhara A, Holt BJ et al. Regulation of Th-cell responses to inhalant allergen during early childhood. Clin Exp Allergy 1999;29: 12231231.
  • 10
    Prescott S, Macaubas C, Holt B, Smallacombe T, Loh R, Sly P et al. Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T-cell responses towards Th-2 cytokine profile. J Immunol 1998;160: 47304737.
  • 11
    Steinborn A, Gunes H, Halberstadt E. Signal for term parturition if of trophoblast and therefore fetal origin. Prostaglandins 1995;50: 237252.
  • 12
    Johansson SG, Hourihane JO, Bousquet J, Bruijnzeel-Koomen C, Dreborg S, Haahtela T et al. A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force. Allergy 2001;56: 813824.
  • 13
    Hanifen J, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol (Stockh) 1980; 92(Suppl. 144):4447.
  • 14
    Dreborg S. The skin prick test: methodological studies and clinical applications. Linköping University Medical Dissertations. Linköping: VTT-Grafiska Vimmerby, 1987.
  • 15
    Prescott SL, Macaubas C, Smallacombe T, Holt BJ, Sly PD, Loh R et al. Reciprocal age-related patterns of allergen-specific T-cell immunity in normal vs. atopic infants. Clin Exp Allergy 1998;28(Suppl. 5):3944; discussion 50–51.
  • 16
    Upham JW, Holt BJ, Baron-Hay MJ, Yabuhara A, Hales BJ, Thomas WR et al. Inhalant allergen-specific T-cell reactivity is detectable in close to 100% of atopic and normal individuals: covert responses are unmasked by serum-free medium. Clin Exp Allergy 1995;25: 634642.
  • 17
    Ng TW, Holt PG, Prescott SL. Cellular immune responses to ovalbumin and house dust mite in egg-allergic children. Allergy 2002;57: 207214.
  • 18
    Holt PG, Rudin A, Macaubas C, Holt BJ, Rowe J, Loh R et al. Development of immunologic memory against tetanus toxoid and pertactin antigens from the diphtheria-tetanus-pertussis vaccine in atopic versus nonatopic children. J Allergy Clin Immunol 2000;105: 11171122.
  • 19
    Williams TJ, Jones CA, Miles EA, Warner JO, Warner JA. Fetal and neonatal IL-13 production during pregnancy and at birth and subsequent development of atopic symptoms. J Allergy Clin Immunol 2000;105: 951959.
  • 20
    Gabrielsson S, Soderlund A, Nilsson C, Lilja G, Nordlund M, Troye-Blomberg M. Influence of atopic heredity on IL-4-, IL-12- and IFN-gamma-producing cells in in vitro activated cord blood mononuclear cells. Clin Exp Immunol 2001;126: 390396.