This overview was adapted from the Ceppellini Lecture given on May 6th 2003 at the 17th European Immunogenetics and Histocompatibility Conference held in Baden-Baden, Germany, and organized by the European Federation for Immunogenetics.
Immunogenetics of killer-cell immunoglobulin-like receptors
Article first published online: 3 SEP 2003
Volume 62, Issue 3, pages 194–200, September 2003
How to Cite
Parham, P. (2003), Immunogenetics of killer-cell immunoglobulin-like receptors. Tissue Antigens, 62: 194–200. doi: 10.1034/j.1399-0039.2003.00126.x
- Issue published online: 3 SEP 2003
- Article first published online: 3 SEP 2003
- Received and accepted for publication 26 July 2003
- innate immunity;
- NK cells
Abstract The immunogenetics of cell-surface antigens began with the study of red cells and then moved onto the white cells. HLA class I antigens were analyzed on leukocytes and HLA class II antigens on B cells. In the last decade the natural killer (NK) cell has become a target for immunogeneticists, in particular the family of genes encoding the killer-cell immunoglobulin-like receptors (KIRs).