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Is 24-h sperm motility a useful IVF measure when male infertility is not apparent?

Authors

  • Mamdoh Eskandar

    1. From the Department of Obstetrics & Gynecology and Reproductive Medicine, King Khalid University, College of Medicine, Abha, Saudi Arabia
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Address for correspondence:
Dr Mamdoh Eskandar
Department of Obstetrics & Gynecology and Reproductive Medicine
College of Medicine
King Khalid University
PO Box 641
Abha
Saudi Arabia
e-mail: mamdoheskandar@hotmail.com

Abstract

Objective.  To examine the relationship of 24-h sperm motility between post insemination and fertilization in vitro, in a population with no apparent semen abnormalities. A retrospective study from July 1998 to June 2000.

Material and methods.  Four hundred and seventy-one consecutive in-vitro fertilization (IVF) cycles for which the primary diagnosis was not male infertility (total motility count > 40 × 106) were studied. Linear regression was used to examine the general relation between 24-h sperm motility and IVF. The cohort with 0% 24-h motility was compared with all other cycles using the t-test and the χ2-test. Test quality was assessed using the positive likelihood ratio.

Results.  Overall fertilization was 58 ± 16%. There were 45/471 cycles (9.5%) with zero fertilization. Linear regression of percent fertilization vs. 24-h motility showed no relationship (r = 0.01). The cohort with 0% 24-h motility had a lower fertilization rate 29 ± 19% (P = 0.05), and had a higher incidence of no fertilization 7/21 (P = 0.01). The positive likelihood ratio was 4.6.

Conclusions.  Zero 24-h motility indicates occult male infertility, and a positive result indicates a fair to good test. Overall there was no relationship between sperm survival at 24 h post insemination and fertilization in vitro. However, 0% 24-h sperm motility was associated with reduced fertilization

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