You have full text access to this OnlineOpen article

Relationship between optic nerve head microcirculation and visual field loss in glaucoma

  1. Kiyoshi Yaoeda1,*,
  2. Motohiro Shirakashi1,
  3. Atsushi Fukushima1,
  4. Shigeo Funaki1,
  5. Haruko Funaki1,
  6. Haruki Abe1,
  7. Naohito Tanabe2

Article first published online: 29 MAY 2003

DOI: 10.1034/j.1600-0420.2003.00073.x

Issue

Acta Ophthalmologica Scandinavica

Acta Ophthalmologica Scandinavica

Volume 81, Issue 3, pages 253–259, June 2003

Additional Information

How to Cite

Yaoeda, K., Shirakashi, M., Fukushima, A., Funaki, S., Funaki, H., Abe, H. and Tanabe, N. (2003), Relationship between optic nerve head microcirculation and visual field loss in glaucoma. Acta Ophthalmologica Scandinavica, 81: 253–259. doi: 10.1034/j.1600-0420.2003.00073.x

Author Information

  1. 1

    Department of Ophthalmology, Faculty of Medicine, Niigata University, Niigata, Japan

  2. 2

    Division of Health Promotion, Department of Community Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

*Kiyoshi Yaoeda MD Department of Ophthalmology Faculty of Medicine Niigata University 1 Asahimachi-dori Niigata City Niigata 951 8510 Japan Tel: + 81 25 227 2296 Fax: + 81 25 227 0785 Email: arasan@med.niigata-u.ac.jp

Publication History

  1. Issue published online: 29 MAY 2003
  2. Article first published online: 29 MAY 2003
  3. Received on December 5th, 2001. Accepted on December 14th, 2002.

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (303K)

Keywords:

  • laser speckle flowgraphy;
  • glaucoma;
  • blood flow;
  • visual field loss

Abstract.

Purpose:  To study the relationship between optic nerve head blood flow velocity and visual field loss in patients with primary open-angle glaucoma (POAG) and normal tension glaucoma (NTG).

Methods:  This study included 44 eyes of 44 patients with POAG and 44 eyes of 44 patients with NTG. To evaluate optic nerve head blood flow velocity, the square blur rate (SBR) was measured by means of laser speckle flowgraphy. The correlation between SBR and Humphrey visual field indices was evaluated with linear regression analysis.

Results:  In the NTG group, the average SBR at the superior and inferior temporal neuroretinal rim was positively correlated with mean deviation (MD) (r = 0.349, p = 0.020). The SBR at the superior or inferior temporal neuroretinal rim was positively correlated with the sum of the total deviations in the corresponding hemifields (r = 0.299, p = 0.049; r = 0.354, p = 0.019, respectively). The correlations between SBR and MD did not differ statistically between the NTG and POAG groups; however, no significant correlation between SBR and visual field indices was observed in the POAG group.

Conclusion:  These results suggested that the change in the circulation of the optic nerve head may be related to visual field damage in the NTG group but may be less involved in visual field damage in the POAG group.

View Full Article (HTML) Get PDF (303K)