Validity of the Hopkins Symptom Checklist-25 amongst HIV-positive pregnant women in Tanzania
Article first published online: 5 JUL 2002
Acta Psychiatrica Scandinavica
Volume 106, Issue 1, pages 9–19, July 2002
How to Cite
Kaaya, S. F. , Fawzi, M. C. S. , Mbwambo, J. K. , Lee, B. , Msamanga, G. I. and Fawzi, W. (2002), Validity of the Hopkins Symptom Checklist-25 amongst HIV-positive pregnant women in Tanzania. Acta Psychiatrica Scandinavica, 106: 9–19. doi: 10.1034/j.1600-0447.2002.01205.x
- Issue published online: 5 JUL 2002
- Article first published online: 5 JUL 2002
- HSCL-25 validation;
- pregnant women and HIV
Objective: To validate the Hopkins Symptom Checklist-25 (HSCL-25) for use as a depression screen amongst human immuno-deficiency virus (HIV) positive pregnant women.
Method: Amongst 903 (mean age 24.8 years) HIV-positive pregnant women, a two-phased design included measures for health-related quality of life, perceived social support, and the HSCL-25 screen for depressive (HSCL-15 subscale) and anxiety symptoms. The Structured Clinical Interview for DSM-IV (SCID) was independently administered on a stratified random subsample.
Results: Internal consistency of the HSCL-25 (alpha 0.93) and HSCL-15 (alpha 0.9) was adequate, with expected findings demonstrated in discriminant validity analysis. A depression-anxiety construct explained nearly 40% of the variance. Eight individual HSCL-25 items demonstrated an area under the curve (AUC) greater than 0.6 for DSM-IV major depression and the HSCL-25 and HSCL-revised had an optimal depression cut-off score of 1.06 and 1.03 for the HSCL-15.
Conclusion: The HSCL-25 demonstrated utility as a screen for depression; its inability to gauge severity of symptoms in this cultural context is discussed.