Gender differences in unipolar depression: an update of epidemiological findings and possible explanations
Article first published online: 31 JUL 2003
Acta Psychiatrica Scandinavica
Volume 108, Issue 3, pages 163–174, September 2003
How to Cite
Kuehner, C. (2003), Gender differences in unipolar depression: an update of epidemiological findings and possible explanations. Acta Psychiatrica Scandinavica, 108: 163–174. doi: 10.1034/j.1600-0447.2003.00204.x
- Issue published online: 31 JUL 2003
- Article first published online: 31 JUL 2003
- Accepted for publication June 2, 2003
- gender differences;
Objective: To give an update on epidemiological findings on sex differences in the prevalence of unipolar depression and putative risk factors.
Material and methods: Systematic review of the literature.
Results: Recent epidemiological research yields additional evidence for a female preponderance in unipolar depression, holding true across different cultural settings. Current explanations include artefacts, genetic, hormonal, psychological and psychosocial risk factors. Rather consistently, intrapsychic and psychosocial gender role related risk factors have been identified which may contribute to the higher depression risk in women. Gender role aspects are also reflected in endocrine stress reactions and possibly influence associated neuropsychological processes.
Conclusion: There is a need for more integrative models taking into account psychological, psychosocial, and macrosocial risk factors as well as their interactions, which also connect these factors with physiological and endocrine responses. Furthermore, it is conceivable that across the life span, as well as across cultural settings, individual risk factors will add with varying emphasis to the higher prevalence of depression in women.