Skin occlusion and irritant and allergic contact dermatitis: an overview
Article first published online: 12 JAN 2002
Volume 44, Issue 4, pages 201–206, April 2001
How to Cite
Zhai, H. and Maibach, H. I. (2001), Skin occlusion and irritant and allergic contact dermatitis: an overview. Contact Dermatitis, 44: 201–206. doi: 10.1034/j.1600-0536.2001.044004201.x
- Issue published online: 12 JAN 2002
- Article first published online: 12 JAN 2002
- Accepted for publication 4 September 2000
- irritant contact dermatitis;
- occlusion, percutaneous absorption-penetration;
- stratum corneum;
- transdermal therapeutic systems;
- transepidermal water loss.
Occlusion, widely used to enhance percutaneous absorption of drugs, also increases penetration of other chemicals and antigens, and hence may exacerbate irritant and allergic contact dermatitis. This overview summarizes the adverse effects of occlusion.