Cutaneous pseudolymphoma in association with molluscum contagiosum in an elderly patient


D. Moreno-Ramírez, Department of Dermatology, Universitary Hospital Virgen Macarena, Avda. Dr. Fedriani s/n. 41073-Seville, Spain


Background:  Molluscum contagiosum (MC) is a common cutaneous infection, which has been reported in association with cutaneous pseudolymphoma in few cases.

Methods:  A 72-year-old woman with a nodule arising on the external canthus was reviewed. The lesion was surgically removed, and the histopathological study demonstrated an epidermal invagination filled by molluscum bodies and a diffuse infiltrate comprising atypical lymphocytes.

Results:  Immunohistochemical stains disclosed predominance of T cells with positive CD30 labeling. Polymerase chain reaction failed to demonstrate clonal rearrangement of the T-cell receptor.

Conclusion:  After ruling out systemic involvement, the patient was followed up for 2 years with no evidence of recurrence. We report this case to the best of our knowledge and discuss the literature about atypical clinical and histological presentations of MC.