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Keywords:

  • Actin;
  • intracellular transport;
  • unconventional myosins;
  • vesicle traffic

The family of unconventional myosins is ever growing and the functions attributed to them seem to expand in parallel. These actin-based motor proteins have been implicated in processes as seemingly diverse as endocytosis and exocytosis, the transport of organelles, in spermatogenesis and in neurosensory functions such as hearing and sight. A common myosin function may underlie them all — the regulation of intracellular membrane traffic.