• 1
    Hosenpud JD, Bennett LE, Keck BM, Boucek MM, Novick RJ. The Registry of the International Society for Heart and Lung Transplantation: seventeenth official report. J Heart Lung Transplant 2000; 19: 909931.
  • 2
    Johnson DE, Alderman EL, Schroeder JS et al. Transplant coronary artery disease: histopathologic correlations with angiographic morphology. J Am Coll Cardiol, 1991; 17: 449457.
  • 3
    Suzuki J, Isobe M, Aikawa M et al. Nonmuscle and smooth muscle myosin heavy chain expression in rejected cardiac allografts. A study in rat and monkey models. Circulation 1996; 94: 11181124.
  • 4
    Hosenpud JD. Immune mechanisms of cardiac allograft vasculopathy: an update. Transpl Immunol 1993; 1: 237249.
  • 5
    Nagano H, Mitchell RN, Taylor MK, Hasegawa S, Tilney NL, Libby P. Interferon-gamma deficiency prevents coronary arteriosclerosis but not myocardial rejection in transplanted mouse hearts. J Clin Invest 1997; 100: 550557.
  • 6
    Nagano H, Libby P, Taylor MK et al. Coronary arteriosclerosis after T-cell-mediated injury in transplanted mouse hearts: role of interferon-gamma. Am J Pathol 1998; 152: 11871197.
  • 7
    Tellides G, Tereb DA, Kirkiles-Smith NC et al. Interferon-gamma elicits arteriosclerosis in the absence of leukocytes. Nature 2000; 403: 207211.
  • 8
    Eigler A, Sinha B, Hartmann G, Endres S. Taming TNF: strategies to restrain this proinflammatory cytokine. Immunol Today 1997; 18: 487492.
  • 9
    Kondo S, Sauder DN. Tumor necrosis factor (TNF) receptor type 1 (p55) is a main mediator for TNF-alpha-induced skin inflammation. Eur J Immunol 1997; 27: 17131718.
  • 10
    Tracey KJ, Cerami A. Tumor necrosis factor: a pleiotropic cytokine and therapeutic target. Annu Rev Med 1994; 45: 491503.
  • 11
    Luster AD. Chemokines – chemotactic cytokines that mediate inflammation. N Engl J Med 1998; 338: 436445.
  • 12
    Peschon JJ, Torrance DS, Stocking KL et al. TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation. J Immunol 1998; 160: 943952.
  • 13
    Bazzoni F, Beutler B. The tumor necrosis factor ligand and receptor families. N Engl J Med 1996; 334: 17171725.
  • 14
    Tartaglia LA, Pennica D, Goeddel DV. Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor. J Biol Chem 1993; 268: 1854218548.
  • 15
    Erickson SL, De Sauvage FJ, Kikly K et al. Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice. Nature 1994; 372: 560563.
  • 16
    Lucas R, Juillard P, Decoster E et al. Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria. Eur J Immunol 1997; 27: 17191725.
  • 17
    Yamada J, Streilein JW, Dana MR. Role of tumor necrosis factor receptors TNFR-I (P55) and TNFR-II (P75) in corneal transplantation. Transplantation 1999; 68: 944949.
  • 18
    Nagano H, Tilney NL, Stinn JL et al. Deficiencies of IL-4 or TNF-alpha receptor-1 do not diminish graft arteriosclerosis in cardiac allografts. Transplant Proc 1999; 31: 152.
  • 19
    Suzuki J, Isobe M, Morishita R et al. Prevention of graft coronary arteriosclerosis by antisense cdk2 kinase oligonucleotide. Nat Med 1997; 3: 900903.
  • 20
    Ono K, Lindsey ES. Improved technique of heart transplantation in rats. J Thorac Cardiovasc Surg 1969; 57: 225229.
  • 21
    Shimizu K, Schonbeck U, Mach F, Libby P, Mitchell RN. Host CD40 ligand deficiency induces long-term allograft survival and donor-specific tolerance in mouse cardiac transplantation but does not prevent graft arteriosclerosis. J Immunol 2000; 165: 35063518.
  • 22
    Furukawa Y, Becker G, Stinn JL, Shimizu K, Libby P, Mitchell RN. Interleukin-10 (IL-10) augments allograft arterial disease: paradoxical effects of IL-10 in vivo. Am J Pathol 1999; 155: 19291939.
  • 23
    Furukawa Y, Mandelbrot DA, Libby P, Sharpe AH, Mitchell RN. Association of B7–1 co-stimulation with the development of graft arterial disease. Studies using mice lacking B7–1, B7–2, or B7–1/B7–2. Am J Pathol 2000; 157: 473484.
  • 24
    Hasegawa S, Becker G, Nagano H, Libby P, Mitchell RN. Pattern of graft- and host-specific MHC class II expression in long- term murine cardiac allografts: origin of inflammatory and vascular wall cells. Am J Pathol 1998; 153: 6979.
  • 25
    Stinn JL, Taylor MK, Becker G et al. Interferon-gamma-secreting T-cell populations in rejecting murine cardiac allografts: assessment by flow cytometry. Am J Pathol 1998; 153: 13831392.
  • 26
    Briones MA, Phillips DJ, Renshaw MA, Hooper WC. Expression of chemokine by human coronary-artery and umbilical-vein endothelial cells and its regulation by inflammatory cytokines. Coron Artery Dis 2001; 12: 179186.
  • 27
    Denk A, Goebeler M, Schmid S et al. Activation of NF-kappa B via the I-kappa B kinase complex is both essential and sufficient for proinflammatory gene expression in primary endothelial cells. J Biol Chem 2001; 276: 2845128458.
  • 28
    Deckert-Schluter M, Bluethmann H, Rang A, Hof H, Schluter D. Crucial role of TNF receptor type 1 (p55), but not of TNF receptor type 2 (p75), in murine toxoplasmosis. J Immunol 1998; 160: 34273436.
  • 29
    Wolf D, Hallmann R, Sass G et al. TNF-alpha-induced expression of adhesion molecules in the liver is under the control of TNFR1 – relevance for concanavalin A-induced hepatitis. J Immunol 2001; 166: 13001307.
  • 30
    Kurrelmeyer KM, Michael LH, Baumgarten G et al. Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. Proc Natl Acad Sci U S A 2000; 97: 54565461.
  • 31
    Schreyer SA, Peschon JJ, LeBoeuf RC. Accelerated atherosclerosis in mice lacking tumor necrosis factor receptor p55. J Biol Chem 1996; 271: 2617426178.
  • 32
    Grenz A, Schenk M, Zipfel A, Viebahn R. TNF-alpha and its receptors mediate graft rejection and loss after liver transplantation. Clin Chem Lab Med 2000; 38: 11831185.
  • 33
    Dorge SE, Roux-Lombard P, Dayer JM, Koch KM, Frei U, Lonnemann G. Plasma levels of tumor necrosis factor (TNF) and soluble TNF receptors in kidney transplant recipients. Transplantation 1994; 58: 10001008.
  • 34
    Scheringa M, De Bruin RW, Jeekel H, Marquet RL. Anti-tumor necrosis factor alpha serum prolongs heart allograft survival in rats. Transplant Proc 1991; 23: 547548.
  • 35
    Hill GR, Teshima T, Rebel VI et al. The p55 TNF-alpha receptor plays a critical role in T cell alloreactivity. J Immunol 2000; 164: 656663.
  • 36
    Lucas R, Garcia I, Donati YR et al. Both TNF receptors are required for direct TNF-mediated cytotoxicity in microvascular endothelial cells. Eur J Immunol 1998; 28: 35773586.
  • 37
    Broide DH, Stachnick G, Castaneda D, Nayar J, Sriramarao P. Inhibition of eosinophilic inflammation in allergen-challenged TNF receptor p55/p75 – and TNF receptor p55-deficient mice. Am J Respir Cell Mol Biol 2001; 24: 304311.
  • 38
    Schmid EF, Binder K, Grell M, Scheurich P, Pfizenmaier K. Both tumor necrosis factor receptors, TNFR60 and TNFR80, are involved in signaling endothelial tissue factor expression by juxtacrine tumor necrosis factor alpha. Blood 1995; 86: 18361841.
  • 39
    Mackay F, Loetscher H, Stueber D, Gehr G, Lesslauer W. Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55. J Exp Med 1993; 177: 12771286.
  • 40
    Murakami T, Mataki C, Nagao C et al. The gene expression profile of human umbilical vein endothelial cells stimulated by tumor necrosis factor alpha using DNA microarray analysis. J Atheroscler Thromb 2000; 7: 3944.
  • 41
    Paleolog EM, Delasalle SA, Buurman WA, Feldmann M. Functional activities of receptors for tumor necrosis factor-alpha on human vascular endothelial cells. Blood 1994; 84: 25782590.
  • 42
    Gerdes N, Sukhova GK, Libby P, Reynolds RS, Young JL, Shoenbeck U. Expression of interleukin (IL) -18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells and macrophages: implications for atherogenesis. J Exp Med 2002; 195: 245257.
  • 43
    Shimizu K, Sugiyama S, Aikawa M et al. Host bone-marrow cells are a source of donor intimal smooth-muscle-like cells in murine aortic transplant arteriopathy. Nat Med 2001; 7: 738741.