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This article describes the development and implementation of the Comprehensive Assessment and Training Services Project, a multidisciplinary center designed to prevent children from lingering in the foster care system and to provide early interventions to prevent lifelong problems. This article outlines the conditions that led to the identified need for such a program; the conceptual model used to guide protocol development and refinement; the methodological approach to evaluation, intervention, and technology transfer; specific program components; and, finally, the challenges and barriers to success.