Rejuvenating Tithonus


  • Kyle M Loh,

    1. Department of Developmental Biology, Stanford University School of Medicine, and the Stanford Institute for Stem Cell Biology & Regenerative Medicine, Stanford, California, USA
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  • Bing Lim

    1. Genome Institute of Singapore, Stem Cell & Developmental Biology Group, Department of Haematology/Oncology, Beth Israel Deaconess Medical Centre and Harvard Medical School, Singapore, Boston, Massachusetts, USA
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Four recent publications, including one in this issue by Surani and colleagues, report that Prdm14 preserves the pluripotent stem cell state by inhibiting FGF signalling and global DNA methylation.