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Synaptic Vesicle Proteins

  1. Andrew J Bean1,
  2. Thomas A Vida2

Published Online: 15 JUL 2003

DOI: 10.1038/npg.els.0000214

eLS

eLS

How to Cite

Bean, A. J. and Vida, T. A. 2003. Synaptic Vesicle Proteins. eLS. .

Author Information

  1. 1

    University of Texas, Houston, Texas, USA

  2. 2

    University of Texas Medical School, Houston, Texas, USA

Publication History

  1. Published Online: 15 JUL 2003

Abstract

Synaptic transmission underlies much of interneuronal communication and is essential for nervous system function. Small vesicles, initially observed by morphological methods, and abundant in the nerve terminal, are filled with neurotransmitters and fuse with the plasma membrane, enabling secretion into the synaptic cleft. In the last 10 years, molecular details of the synaptic vesicle life cycle have emerged, allowing a more complete understanding of neurotransmitter secretion.

Keywords:

  • vesicle;
  • synapse;
  • SNARE;
  • synaptic transmission