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Adeno-associated Viruses

  1. Xiao Xiao

Published Online: 20 JUN 2001

DOI: 10.1038/npg.els.0000408

Book Title

eLS

eLS

Additional Information

How to Cite

Xiao, X. 2001. Adeno-associated Viruses. eLS. .

Author Information

  1. University of Pittsburgh, Pittsburgh, Pennsylvania, USA

Publication History

  1. Published Online: 20 JUN 2001
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Abstract

Adeno-associated viruses are small, nonenveloped, single-stranded viruses of the genus Dependovirus, family Parvoviridae. They are so named because their propagation depends upon the coinfection by an unrelated virus for essential helper functions.

Keywords:

  • parvoviridae;
  • AAV;
  • episomal persistence;
  • recombinant viral vector;
  • vector production;
  • gene therapy;
  • rep proteins;
  • hairpin transfer replication;
  • site-specific integration
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