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Nucleotide Excision Repair in Eukaryotes

  1. Errol C Friedberg

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0000562

eLS

eLS

How to Cite

Friedberg, E. C. 2001. Nucleotide Excision Repair in Eukaryotes. eLS. .

Author Information

  1. University of Texas Southwestern Medical Center, Dallas, Texas, USA

Publication History

  1. Published Online: 19 APR 2001

Abstract

Nucleotide excision repair is the process whereby eukaryotic cells repair damaged DNA by the excision of damaged bases as oligonucleotide fragments. Several genes have been identified as expressing proteins important for the repair mechanism and have therefore been implicated in the related human hereditary diseases.

Keywords:

  • DNA repair;
  • nucleotide excision repair;
  • yeast;
  • human eukaryotes;
  • DNA damage