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DNA Repair by Reversal of Damage

  1. Asli Memisoglu1,
  2. Leona D Samson2

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0000579

eLS

eLS

How to Cite

Memisoglu, A. and Samson, L. D. 2001. DNA Repair by Reversal of Damage. eLS. .

Author Information

  1. 1

    Harvard School of Public Health, Boston, Massachusetts, USA

  2. 2

    Harvard School of Public Health, Boston, Massachusetts, USA

Publication History

  1. Published Online: 19 APR 2001

Abstract

Some DNA repair mechanisms involve the simple reversal of DNA damage. These processes require a single protein that is able first to recognize DNA damage, and then to catalyse the reversal of damage to the DNA, thus restoring the DNA to its original state.

Keywords:

  • DNA damage;
  • DNA repair;
  • photolyase;
  • O6-methylguanine DNA repair methyltransferase;
  • photoreactivation