Homologous Genetic Recombination in Eukaryotes
Published Online: 19 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Sung, P. 2001. Homologous Genetic Recombination in Eukaryotes. eLS.
- Published Online: 19 APR 2001
In eukaryotes, homologous recombination is mediated by genes of the RAD52 epistasis group. Several products of the RAD52 group genes function together to catalyse the homologous DNA pairing and strand exchange reaction that establishes a stable linkage between the recombining chromosomes.
- RAD52 group proteins;
- homologous DNA pairing and strand exchange;
- genome stability;
- tumour suppression