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Rad51 and Eukaryotic Recombination Proteins

  1. Eugene L Ivanov

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0000585

eLS

eLS

How to Cite

Ivanov, E. L. 2001. Rad51 and Eukaryotic Recombination Proteins. eLS. .

Author Information

  1. Transkaryotic Therapies, Inc., Cambridge, Massachusetts, USA

Publication History

  1. Published Online: 19 APR 2001

Abstract

Recombination proteins in eukaryotic cells function to provide genetic diversity and to maintain stability of the genome. They demonstrate high levels of structural and functional homology with each other and with those of prokaryotic organisms, suggesting that fundamental mechanisms of genetic recombination are conserved throughout the evolution.

Keywords:

  • Rad51;
  • RecA;
  • homologous recombination;
  • recombinational DNA repair