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RecBCD Helicase/Nuclease

  1. Deana A Arnold,
  2. Stephen C Kowalczykowski

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0000586

eLS

eLS

How to Cite

Arnold, D. A. and Kowalczykowski, S. C. 2001. RecBCD Helicase/Nuclease. eLS. .

Author Information

  1. University of California, Davis, California, USA

Publication History

  1. Published Online: 19 APR 2001

Abstract

The RecBCD enzyme of Escherichia coli participates in several aspects of DNA recombination and repair. It is essential to the main pathway of genetic homologous recombination, where it contributes to the exchange of genetic material between homologous DNA molecules (i.e. conjugal recombination), and to the recombinational repair of potentially lethal chromosomal double-stranded breaks.

Keywords:

  • RecBCD;
  • recombination;
  • hotspot;
  • DNA repair;
  • E. coli