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Enzyme Activity: Reversible Inhibition

  1. John F Morrison

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0000600

eLS

eLS

How to Cite

Morrison, J. F. 2001. Enzyme Activity: Reversible Inhibition. eLS. .

Author Information

  1. Australian National University, Canberra, Australia

Publication History

  1. Published Online: 19 APR 2001

Abstract

Data for the inhibition of enzyme-catalysed reactions by substrate analogues provide inhibition patterns that are helpful for the elucidation of kinetic mechanisms. Analysis of such data yields values for true inhibition constants that give a measure of the strength of interaction between the enzyme and the inhibitor.

Keywords:

  • enzyme inhibition;
  • kinetic mechanisms;
  • rate equations;
  • inhibition constants;
  • inhibition patterns