Standard Article

Binding Constants: Measurement and Biological Range

  1. Donald J Winzor

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0000615

eLS

eLS

How to Cite

Winzor, D. J. 2001. Binding Constants: Measurement and Biological Range. eLS. .

Author Information

  1. University of Queensland, Brisbane, Australia

Publication History

  1. Published Online: 19 APR 2001

Abstract

Several methods exist for the measurement of binding constants for macromolecular interactions between dissimilar reactants. These allow biological interactions with binding constants in the range 102 to 109 mol L−1 to be characterized quantitatively.

Keywords:

  • equilibrium interactions;
  • reaction thermodynamics;
  • ligand–acceptor (receptor) interactions