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Enzymatic Free Radical Reactions

  1. Squire J Booker

Published Online: 3 MAY 2005

DOI: 10.1038/npg.els.0000620



How to Cite

Booker, S. J. 2005. Enzymatic Free Radical Reactions. eLS. .

Author Information

  1. Pennsylvania State University, University Park, Pennsylvania, USA

Publication History

  1. Published Online: 3 MAY 2005


Nature has evolved an array of cofactors to aid in the initiation of enzymatic reactions that take place via mechanisms involving unpaired electrons centred on carbon atoms. A unifying theme among many of these cofactors is that they contain metal atoms that participate intimately in the radical-generation process.


  • radicals;
  • S-adenosylmethionine;
  • adenosylcobalamin;
  • ribonucleotide reductase;
  • quinones;
  • monooxygenases;
  • eicasanoids;
  • leukotrienes;
  • iron–sulfur clusters