Published Online: 25 JUL 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Nielsen, J. 2001. Metabolic Turnover. eLS. .
- Published Online: 25 JUL 2001
Metabolic turnover is the sum of all biochemical reactions – the metabolic network – within a living cell that are involved in the conversion of substrates, particularly carbon, nitrogen and energy sources into Gibbs free energy, secreted metabolites and cell mass. Analysis of metabolic turnover involves identification of which reactions are active in a cell, and of quantifying the fluxes carried by the branches of the network and elucidating how these fluxes are controlled. Control of fluxes takes place at many levels, but the usual distinction is between global and local control.
- metabolic flux analysis;
- metabolic control analysis;
- biochemical pathways;
- enzyme kinetics;
- enzyme regulation