Enzymes: Coenzyme A dependent
Published Online: 21 AUG 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Shoolingin-Jordan, P. M. and Crump, M. P. 2001. Enzymes: Coenzyme A dependent. eLS. .
- Published Online: 21 AUG 2001
A large group of unrelated enzymes involved in primary and secondary metabolism utilize a thiol group to form acyl thiol esters. The enzymes form noncovalent interactions with the coenzyme A moiety and utilize the ketonic properties of the thiol ester to facilitate acyl transfer and nucleophilic activation.
- coenzyme A (CoA)-dependent enzymes;
- thiol ester;
- C–C bond formation;
- acyl group transfer